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  1. The Oxford–AstraZeneca COVID‑19 vaccine is used to provide protection against infection by the SARS-CoV-2 virus in order to prevent COVID-19 in adults aged 18 years and older. [1] The medicine is administered by two 0.5 ml (0.017 US fl oz) doses given by intramuscular injection into the deltoid muscle (upper arm).

  2. The COVID-19 pandemic, also known as the coronavirus pandemic, is a global pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The novel virus was first identified in an outbreak in Wuhan, the capital of Hubei, China, in December 2019, before it spread to other areas of Asia, and then worldwide in early 2020.

  3. en.wikipedia.org › wiki › RimonabantRimonabant - Wikipedia

    • History
    • Adverse Effects
    • Pharmacology
    • Research
    • See Also

    Rimonabant is a selective CB1 receptor blocker and was discovered and developed by Sanofi-Aventis. On 21 June 2006, the European Commission approved the sale of rimonabant in the then-25-member European Union as a prescription drug for use in conjunction with diet and exercise for patients with a body mass index (BMI) greater than 30 kg/m2, or pati...

    Data from clinical trials submitted to regulatory authorities showed that rimonabant caused depressive disorders or mood alterations in up to 10% of subjects and suicidal ideation in around 1%, and in Europe it was contraindicated for people with any psychiatric disorder, including depressed or suicidal individuals.Data from a large, randomized, cl...

    Pharmacodynamics

    Rimonabant is an inverse agonist of the cannabinoid CB1 receptor. Originally thought to be selective for the CB1 receptor, rimonabant was subsequently also found to act as an antagonist of the μ-opioid receptor.

    Along with the clinical trials in obesity that generated the data submitted to regulatory authorities, rimonabant was also studied in clinical trialsfor diabetes, atherosclerosis, and smoking cessation.

    Drinabant– a cannabinoid receptor antagonist developed for prescription drug use that triggered severe psychiatric side effects.

  4. Narendra Damodardas Modi ( Gujarati: [ˈnəɾendɾə dɑmodəɾˈdɑs ˈmodiː] ⓘ; born 17 September 1950) [b] is an Indian politician who has served as the 14th prime minister of India since May 2014. Modi was the chief minister of Gujarat from 2001 to 2014 and is the Member of Parliament (MP) for Varanasi. He is a member of the Bharatiya ...

  5. en.wikipedia.org › wiki › ParacetamolParacetamol - Wikipedia

    Paracetamol (acetaminophen[a]) is a non-opioid analgesic and antipyretic agent used to treat fever and mild to moderate pain.[13][14][15] It is a widely used over the counter medication. Common brand names include Tylenol and Panadol. At a standard dose, paracetamol only slightly reduces fever;[14][16][17] it is inferior to ibuprofen in that ...

  6. en.wikipedia.org › wiki › Luka_ModrićLuka Modrić - Wikipedia

    Luka Modrić ( Croatian pronunciation: [lûːka mǒːdritɕ]; [4] [5] born 9 September 1985) is a Croatian professional footballer who plays as a midfielder for La Liga club Real Madrid and captains the Croatia national team. He plays mainly as a central midfielder, but can also play as an attacking midfielder or as a defensive midfielder.

  7. George Town is the capital of the Malaysian state of Penang, encompassing Penang Island and surrounding islets. With a population of 794,313 as of the 2020 census, it is the core city of Malaysia's second-largest metropolitan area, which has a population of 2.84 million. George Town serves as the commercial centre for northern Malaysia.