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  1. 2023年8月22日 · slow or irregular heart rate. Common metformin side effects may include: low blood sugar; nausea, upset stomach; or. diarrhea. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. Metformin side effects (more detail)

  2. Check with your doctor immediately if any of the following side effects occur while taking metformin: More common. abdominal or stomach discomfort. cough or hoarseness. decreased appetite. diarrhea. fast or shallow breathing. fever or chills. general feeling of discomfort.

  3. 2023年7月13日 · Metformin increases the ability of cells to uptake glucose by improving their insulin sensitivity. It also works by decreasing the amount of glucose made by the liver and decreasing the absorption of glucose from the intestine. Metformin belongs to the class of drugs known as biguanides. 2. Upsides.

  4. 2024年4月23日 · Maximum dose: 2550 mg/day. Initial dose: 500 to 1000 mg orally once a day. Dose titration: Increase in 500 mg increments weekly as tolerated. Maximum dose: 2000 mg/day. Metformin, if not contraindicated, should be considered first line-therapy for the management of type 2 diabetes mellitus.

  5. 2024年10月21日 · Metformin hydrochloride is a white to off-white crystalline compound with a molecular formula of C 4 H 11 N 5 ∙ HCl and a molecular weight of 165.63. It is freely soluble in water and is practically insoluble in acetone, ether, and chloroform. The pKa of metformin is 12.4.

  6. Metformin Interactions There are 369 drugs known to interact with metformin , along with 5 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 24 are major, 336 are moderate, and 9 are minor.

  7. Initial dosage of 500 mg once daily has been suggested by some experts. Increase daily dosage by 500 mg at weekly intervals or by 850 mg at biweekly (every 2 week) intervals up to a maximum of 2.55 g daily given in divided doses. May increase dosage from 500 mg twice daily to 850 mg twice daily after 2 weeks.

  8. 2023年6月6日 · Metformin lowers blood glucose (sugar) in your body by lowering liver glucose production, reducing intestinal glucose absorption and improving how well your own insulin works. Metformin (brand name: Glumetza) in the biguanide drug class, is usually the first drug used to help control blood sugar in people with type 2 diabetes.

  9. 2024年2月19日 · Common type 2 diabetes medicines include: Metformin (Fortamet) Sulfonylureas, such as glipizide (Glucotrol), glimepiride (Amaryl), or glyburide (Diabeta) Meglitinides, such as repaglinide (Prandin) or nateglinide (Starlix) Thiazolidinediones, such as pioglitazone (Actos) or rosiglitazone. DPP-4 inhibitors, such as sitagliptan (Januvia) or ...

  10. 2024年2月28日 · The chance may be raised when this medicine (metformin extended-release tablets) is used with other drugs for diabetes. Signs may be dizziness, headache, feeling sleepy or weak, shaking, fast heartbeat, confusion, hunger, or sweating. Call your doctor right away if you have any of these signs.

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