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2. 分佈：Rosuvastatin被肝臟大量攝入，而肝臟是膽固醇合成及LDL-膽固醇清除的主要部位。Rosuvastatin的分佈體積約134公升，大概90%的rosuvastatin會與血漿蛋白質結合，主要是與白蛋白結合。3. 代謝：Rosuvastatin的代謝有限（約10%）。
您可以在Hello醫師上發現並參考更多關於Rosuvastatin的資訊，包括它的功效原理、潛在的副作用、潛在的交互作用、醫師建議的使用劑量，以及使用時要小心的注意事項與禁忌。.
上次更新時間：2024/01》. ROSUVASTATIN CALCIUM的用量、作用機轉、副作用、懷孕及哺乳用藥與藥物交互作用，ROSUVASTATIN CALCIUM適應症:高膽固醇血症、高三酸甘油酯血症。.
- What Is Rosuvastatin?
- What Is Rosuvastatin Used for?
- Who Should Not Take Rosuvastatin?
- What Should I Tell My Doctor Before Taking Rosuvastatin?
- How Should I Take Rosuvastatin?
- What Happens If I Miss A dose?
- What Happens If I Overdose?
- Dosing Information
- What Are The Side Effects of Rosuvastatin?
- Interactions
Rosuvastatin (Crestor, Ezallor Sprinkle) is a prescription medication used to treat high cholesterol and prevent heart attacks and strokes. Rosuvastatin belongs to a class of drugs called statins. It works in two ways. Rosuvastatin works by blocking an enzyme in the liver called HMG-CoA reductase, which leads to the liver making less cholesterol. I...
Rosuvastatin tablets are used along with diet to: 1. lower the level of your “bad” cholesterol (low-density lipoprotein, LDL) 2. increase the level of your “good” cholesterol (high-density lipoprotein, HDL) 3. lower the level of fat in your blood (triglycerides) 4. slow the buildup of fatty deposits (plaque) in the walls of blood vessels Rosuvastat...
Do not take rosuvastatin if you: 1. are allergic to rosuvastatin calcium or any of the ingredients in your rosuvastatin tablet or capsule. See below for a complete list of ingredients. 2. have liver problems.
Before taking rosuvastatin, tell your healthcare provider about all or your medical conditions, including if you: 1. have unexplained muscle aches or weakness 2. have or have had kidney problems 3. have or have had liver problems 4. drink more than 2 glasses of alcohol daily 5. have thyroid problems Also tell your healthcare provider if you are 65 ...
How should I take rosuvastatin tablets:
1. Take the tablets exactly as your doctor tells you to take it. 2. Take the tablets by mouth, 1 time each day. Swallow the tablet whole. 3. The tablets can be taken at any time of day, with or without food. 4. Do not change your dose or stop this medication without talking to your doctor, even if you are feeling well. 5. Your doctor may do blood tests to check your cholesterol levels before and during your treatment with rosuvastatin. Your doctor may change your dose of it if needed. 6. Your...
How should I take rosuvastatin capsules:
1. Take the capsules exactly as your doctor tells you to take it. 2. Take the capsules by mouth, 1 time each day. Swallow the capsules whole. 3. Do not crush or chew the capsules. 4. The capsules can be taken at any time of day, with or without food. 5. Taking rosuvastatin capsules with soft food If you have trouble swallowing a whole capsule, you can open the capsule and take the contents with soft food (applesauce, or chocolate- or vanilla-flavored pudding). See the “Instructions for Use” t...
If you miss a dose of rosuvastatin, take it as soon as you remember. However, do not take 2 doses within 12 hours of each other.
If you take too much rosuvastain or overdose, call your doctor or go to the nearest hospital emergency room right away.
Rosuvastatin tablets:
1. Dose range:5-40 mg once daily. Use 40 mg dose only for patients not reaching LDL cholesterol goal with 20 mg. 2. Adults with homozygous familial hypercholesterolemia:Starting dose 20 mg/day. 3. Pediatric patients with homozygous familial hypercholesterolemia:20 mg/day for patients 7 to 17 years of age. 4. Pediatric patients with heterozygous familial hypercholesterolemia:5 to 10 mg/day for patients 8 to less than 10 years of age, and 5 to 20 mg/day for patients 10 to 17 years of age.
Rosuvastatin capsules:
1. Dose range:5 mg to 40 mg once daily. Use 40 mg dose only for patients not reaching LDL cholesterol goal with 20 mg. 2. Adults with homozygous familial hypercholesterolemia:Starting dose 20 mg/day.
Serious side effects of rosuvastatin include: 1. Muscle pain, tenderness and weakness (myopathy). Muscle problems, including muscle breakdown, can be serious in some people and rarely cause kidney damage that can lead to death. Tell your doctor right away if: 1.1. you have unexplained muscle pain, tenderness, or weakness, especially if you have a f...
Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Talk to your doctor before you start taking any new medicines. Taking rosuvastatin with certain other medicines may affect each other causing side effects. Especially tell your doctor if you take: 1. cyclospori...
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- Consultant Pharmacist
瑞舒伐他汀（英語： Rosuvastatin ），商品名為Crestor，中文商品名在中國大陸為可定、在台灣為冠脂妥，是一種他汀類藥物，與運動、飲食控制和減肥聯合來治療高膽固醇血症和其他相關症狀，也用來預防心血管疾病。
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rosuvastatin的代謝產物為何?
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Crestor與rosuvastatin併用期間,Cmax和AUC會增加多少?
史他汀 (Statins) 類藥物包含Rosuvastatin（冠脂妥）、Atorvastatin（立普妥）、Fluvastatin（益脂可）、Simvastatin（維妥力）、Pravastatin（普脂芬）等，是醫師最常開立的處方藥，主要抑制肝臟再製造膽固醇，進而減少血中的膽固醇與三酸甘油脂的含量。
Like all statins, rosuvastatin works by inhibiting HMG-CoA reductase, an enzyme found in the liver that plays a role in producing cholesterol. Rosuvastatin was patented in 1991, and approved for medical use in the United States in 2003. It is available as a .
