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home drug interactions checker. Type in a generic or a brand name drug and select from the list. Add as many prescription drugs or OTC drugs as you'd like. When you're done, check for possible drug interactions. Drug Name: Drug Interaction Categories. Contraindicated.
2023年6月19日 · Orilissa (elagolix) is a gonadotropin-releasing hormone (GnRH) receptor antagonist indicated for the management of moderate to severe pain associated with endometriosis. What Are Side Effects of Orilissa? Orilissa may cause serious side effects including: hives, difficulty breathing, swelling of your face, lips, tongue, or throat,
2022年9月22日 · Ella (ulipristal acetate) is an emergency contraceptive used to prevent pregnancy in emergencies (unprotected sex, barrier contraceptive failure) by preventing ovarian egg release or egg implantation in the uterus. Ella is available in a generic form termed ulipristal acetate. Ella should not be used as a routine contraceptive.
Medications and prescription drug information for consumers and medical health professionals. Online database of the most popular drugs and their side effects, interactions, and use. Top Searched Drugs Lexapro (Escitalopram Oxalate) Coreg (Carvedilol) Macrobid
Protonix Delayed-Release Oral Suspension and Delayed-Release Tablets (pantoprazole sodium) is a proton pump inhibitor (PPI) used for short-term treatment (less than 10 days) of gastroesophageal reflux disease ( GERD) and a history of erosive esophagitis in adult patients. What Are Side Effects of Protonix?
- Mechanism of Action
- Pharmacokinetics
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- Drug Interaction Studies
- Animal Toxicology and/or Pharmacology
- Adults with Mildly to Moderately Active Ulcerative Colitis
The mechanism of action of mesalamine is not fully understood, but it appears to have a topical anti-inflammatory effect on the colonic epithelial cells. Mucosal production of arachidonic acid metabolites, both through the cyclooxygenase and lipoxygenase pathways, is increased in patients with ulcerative colitis, and it is possible that mesalamine ...
The total absorption of mesalamine from LIALDA 2.4 g or 4.8 g given once daily for 14 days to healthy subjects was found to be approximately 21% to 22% of the administered dose. Gamma-scintigraphy studies have shown that a single dose of LIALDA 1.2 g (one tablet) passed intact through the upper gastrointestinal tract of fasted healthy subjects. Sci...
In a single-dose pharmacokinetic study of LIALDA, 4.8 g was administered in the fasted state to 71 healthy male and female subjects (28 young (18-35 years); 28 elderly (65-75 years); 15 elderly (>75 years)). Increased age resulted in increased systemic exposure (approximately 2-fold in Cmax) to mesalamine and its metabolite N-acetyl-5-aminosalicyli...
The potential effect of LIALDA (4.8 g given once daily) on the pharmacokinetics of four commonly used antibiotics were evaluated in healthy subjects. The four antibiotics studied and their dosing regimens were as follows: amoxicillin (single 500-mg dose), ciprofloxacin XR (single 500-mg dose), metronidazole (750 mg twice daily for 3.5 days), and su...
In animal studies with mesalamine, a 13-week oral toxicity study in mice and 13-week and 52-week oral toxicity studies in rats and cynomolgus monkeys have shown the kidney to be the major target organ of mesalamine toxicity. Oral daily doses of 2400 mg/kg in mice and 1150 mg/kg in rats produced renal lesions including granular and hyaline casts, tu...
Two similarly designed, randomized, double-blind, placebo-controlled trials (Study 1, NCT00503243 and Study 2, NCT00548574) were conducted in 517 adult patients with mildly to moderately active ulcerative colitis. The study population was primarily Caucasian (80%), had a mean age of 42 years (6% age 65 years or older), and was approximately 50% mal...
2022年2月8日 · Drug Summary. What Is Codeine Phosphate? Codeine phosphate is an opioid analgesic (pain reliever) drug used to treat many causes of mild to moderate pain. Codeine phosphate is available in generic form. What Are Side Effects of Codeine Phosphate? Common side effects of codeine phosphate include: drowsiness, lightheadedness, dizziness, sedation,
