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Vitamin B12, also known as cobalamin, is a water-soluble vitamin involved in metabolism. [2] It is one of eight B vitamins. It is required by animals, which use it as a cofactor in DNA synthesis, and in both fatty acid and amino acid metabolism. [3]
In molecular biology, the vitamin B12-binding domain is a protein domain which binds to cobalamin (vitamin B12). It can bind two different forms of the cobalamin cofactor, with cobalt bonded either to a methyl group (methylcobalamin) or to 5'-deoxyadenosine
Serum vitamin B12 is a medical laboratory test that measure vitamin B 12 only in the blood binding to both transcobalamins. [1] . Most of the time, 80–94% of vitamin B 12 in the blood binds to haptocorrin, while only 6–20% is binds to transcobalamin ll. [2] Only transcobalamin ll is "active" and can be used by the body. [1] .
B vitamins are a class of water-soluble vitamins that play important roles in cell metabolism and synthesis of red blood cells. [1] [2] They are a chemically diverse class of compounds. Dietary supplements containing all eight are referred to as a vitamin B complex.
Pernicious anemia is the most common cause of clinically evident vitamin B 12 deficiency worldwide. [14] Pernicious anemia due to autoimmune problems occurs in about one per 1000 people in the US. Among those over the age of 60, about 2% have the condition. [8]
fat 900 μg/700 μg night blindness, hyperkeratosis, and keratomalacia hypervitaminosis A from animal origin as vitamin A / all-trans-retinol: fish in general, liver and dairy products; from plant origin as provitamin A / all-trans-beta-carotene: orange, ripe yellow fruits, leafy vegetables, carrots, pumpkin, squash, spinach
Vitamin B12 deficiency Vitamin B12 total synthesis This page was last edited on 7 September 2019, at 03:49 (UTC). Text is available under the Creative Commons Attribution-ShareAlike License 4.0; additional terms may apply. By using this site, you agree to ...
