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  1. Alogliptin with metformin hydrochloride tablets can cause serious side effects, including: 1. Lactic Acidosis. Metformin, one of the medicines in alogliptin with metformin hydrochloride tablets, can cause a rare but serious condition called lactic acidosis (a buildup of an acid in the blood) that can cause death.

  2. 2023年9月4日 · It’s not fully clear why metformin causes diarrhea as a side effect. Researchers believe it could be due to the following reasons: A change in gut microbiome. Increased bile acid concentration in the intestines. Increase in glucagon-like peptide 1 (GLP-1) concentration. Higher amount of serotonin activity in the intestines.

  3. 2023年5月22日 · Adult Dosage. GLUCOPHAGE. The recommended starting dose of GLUCOPHAGE is 500 mg orally twice a day or 850 mg once a day, given with meals. Increase the dose in increments of 500 mg weekly or 850 mg every 2 weeks on the basis of glycemic control and tolerability, up to a maximum dose of 2550 mg per day, given in divided doses.

  4. Januvia has an average rating of 4.6 out of 10 from a total of 138 ratings on Drugs.com. 30% of reviewers reported a positive effect, while 50% reported a negative effect. Metformin has an average rating of 6.9 out of 10 from a total of 645 ratings on Drugs.com. 56% of reviewers reported a positive effect, while 19% reported a negative effect.

  5. 2011年9月15日 · Mallinckrodt Inc., 675 McDonnell Blvd. Hazelwood, MO 63042 Contact Details Phone: (314) 654-2000 Teva Pharmaceuticals , 1090 Horsham Rd. P.O.B. 1090, North Wales, PA 19454 Contact Details Phone: (888) 838-2872 Mylan Inc., 1500 Corporate Drive

  6. 2024年2月29日 · Warning. Rarely, metformin may cause an acid health problem (lactic acidosis). The risk is higher in people who have kidney problems, liver problems, heart failure, use alcohol, or take other drugs like topiramate. The risk is also higher in older people (65 or older) and in people who are having surgery, an exam or test with contrast, or other ...

  7. 2024年4月26日 · Usual Adult Dose for Heart Failure. Initial dose: Dapagliflozin 5 mg plus current metformin dose orally once a day. Dapagliflozin 10 mg plus current metformin dose orally once a day. Maximum dose: Dapagliflozin 10 mg-metformin 2000 mg per day. Comments: Adjust doses based on effectiveness and tolerability.