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3 天前 · SARS-CoV-2 is a positive-sense single-stranded RNA virus. It is contagious in humans and is the cause of the coronavirus disease 2019 (COVID-19). Latest Research and Reviews
3 天前 · SARS, highly contagious respiratory illness characterized by a persistent fever, headache, and bodily discomfort, followed by a dry cough that may progress to great difficulty in breathing. SARS first appeared in November 2002 in Guangdong province, China, and a specific vaccine for it has not yet been developed.
- The Editors of Encyclopaedia Britannica
2 天前 · The history of coronaviruses is an account of the discovery of the diseases caused by coronaviruses and the diseases they cause. It starts with the first report of a new type of upper-respiratory tract disease among chickens in North Dakota, U.S., in 1931. The causative agent was identified as a virus in 1933.
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1 天前 · The so-called FLiRT variants of SARS-CoV-2 coronavirus that cause COVID-19 have been the dominant forms of the virus circulating this year globally, according to the World
4 天前 · SARS-CoV MA15 infection causes mortality in BALB/c mice (37). We observed a time- and dose-dependent effect on survival, with 100% and 70% survival in the GS-5245 groups at 30 and 10 mg/kg at 12 hpi, respectively (Fig. 4D). Delay of treatment initiation in ...
1 天前 · Pathogen genomics can provide insights into disease transmission patterns, but new methods are needed to handle modern large-scale pathogen genome datasets. Genetically proximal viruses indicate epidemiological linkage and are informative about transmission events. Here, we leverage pairs of identical sequences using 114,298 SARS-CoV-2 genomes collected via sentinel surveillance from March ...
5 天前 · There are several key stages in the SARS‑CoV‑2 life cycle, including binding, entry, proteolysis, RNA replication, and exit. 1,3,4 Understanding the full viral life cycle may shed light on current therapies and potential therapeutic targets at each stage. 2,3
