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Zaire ebolavirus, more commonly known as Ebola virus (/ i ˈ b oʊ l ə, ɪ-/; EBOV), is one of six known species within the genus Ebolavirus. Four of the six known ebolaviruses, including EBOV, cause a severe and often fatal hemorrhagic fever in humans and other mammals , known as Ebola virus disease (EVD).
EBOV, species Zaire ebolavirus, is the most dangerous of the known EVD-causing viruses, and is responsible for the largest number of outbreaks. [45] The fifth and sixth viruses, Reston virus (RESTV) and Bombali virus (BOMV), [46] are not thought to cause disease in humans, but have caused disease in other primates.
- Ebolaviruses spread by direct contact
- Supportive care
- Atoltivimab/maftivimab/odesivimab (Inmazeb)
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What is Zaire ebolavirus?
How many people died from Ebola in Zaire?
Which genus causes Ebola virus disease (EVD) in humans?
Why was Ebola renamed 'Ebola virus'?
Five characterised species of the genus Ebolavirus are: Zaire ebolavirus (ZEBOV) Also known simply as the Zaire virus, ZEBOV has the highest case-fatality rate, up to 90% in some epidemics, with an average case fatality rate of approximately 83% over 27
Ebola virus disease is caused by four of six viruses classified in the genus Ebolavirus. Of the four disease-causing viruses, Ebola virus (formerly and often still called the Zaire Ebola virus) is dangerous and is the virus responsible for the epidemic in Western Africa.
- December 2013 – June 2016
As of 2022, there are only vaccines against the Zaire ebolavirus. The first vaccine to be approved in the United States was rVSV-ZEBOV in December 2019. [8] [9] It had been used extensively in the Kivu Ebola epidemic under a compassionate use protocol. [10]
- Ervebo, Zabdeno, Mvabea
- Ebola virus
- US: ℞-only, EU: Rx-only
- Viral vector
1976 Zaire Ebola virus outbreak 2014 DR Congo outbreak Kivu Ebola epidemic List of epidemics and pandemics
1976 Zaire Ebola virus outbreak. 1976 Zaire Ebola virus outbreak. Zaire (orthographic projection) Date. August–November 1976. Casualties. Cases / Deaths: (as at end of outbreak) Zaire: 318 / 280. In August–November 1976, an outbreak of Ebola virus disease occurred in Zaire (now the Democratic Republic of the Congo ).
