維他命b12的功效 相關
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What is vitamin B12 deficiency?
What is vitamin B 12 & why is it important?
What is a vitamin B12 transporting ATPase?
What is a pseudovitamin b 12?
As a supplement it is used to treat vitamin B12 deficiency including pernicious anemia. Other uses include treatment for cyanide poisoning, Leber's optic atrophy, and toxic amblyopia. It is given by injection into a muscle or vein. Side effects are generally few.
- C₆₂H₈₉CoN₁₃O₁₅P
- Very high (90%)
- Primarily liver, cobalamins are absorbed in the ileum and stored in the liver.
- IM, IV
Adenosylcobalamin (AdoCbl), also known as coenzyme B12, cobamamide, and dibencozide, is, along with methylcobalamin (MeCbl), one of the biologically active forms of vitamin B 12. [1] Adenosylcobalamin participates as a cofactor in radical-mediated 1,2-carbon skeleton rearrangements. These processes require the formation of the deoxyadenosyl ...
- C₇₂H₁₀₀CoN₁₈O₁₇P
- Oral
- 1579.608 g·mol−1
- US: OTC
Vitamin B12, also known as cobalamin, is a water-soluble vitamin involved in metabolism. [2] It is one of eight B vitamins. It is required by animals, which use it as a cofactor in DNA synthesis, and in both fatty acid and amino acid metabolism. [3]
- Readily absorbed in distal half of the ileum.
- liver
- C₆₃H₈₈CoN₁₄O₁₄P
6% (< 60 years old), 20% (> 60 years old) [4] Vitamin B12 deficiency, also known as cobalamin deficiency, is the medical condition in which the blood and tissue have a lower than normal level of vitamin B 12. [5] Symptoms can vary from none to severe. [1] Mild deficiency may have few or absent symptoms. [1]
- Poor absorption, decreased intake, increased requirements
- Supplementation by mouth or injection
- Blood levels below 148–185 pmol/L (200–250 pg/mL) in adults
The molecule X-ray crystal structure of Vitamin B 12 (cyanocobalamin) hydrate (Dorothy Hodgkin et al. 1954) Vitamin B 12, C 63 H 88 CoN 14 O 14 P, is the most complex of all known vitamins.Its chemical structure had been determined by x-ray crystal structure analysis in 1956 by the research group of Dorothy Hodgkin (Oxford University) in collaboration with Kenneth N. Trueblood at UCLA and John ...
Cyanocobalamin is a form of vitamin B. 12 used to treat and prevent vitamin B. 12 deficiency except in the presence of cyanide toxicity. [7] [8] [2] The deficiency may occur in pernicious anemia, following surgical removal of the stomach, with fish tapeworm, or due to bowel cancer. [9] [5] It is used by mouth, by injection into a muscle, or as ...
cobalamin-transporting ATPase. In enzymology, a vitamin B12-transporting ATPase ( EC 3.6.3.33) is an enzyme that catalyzes the chemical reaction. The 3 substrates of this enzyme are ATP, H 2 O, and vitamin B 12, whereas its 3 products are ADP, phosphate, and vitamin B 12 .
