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Paracetamol (acetaminophen[a]) is a non-opioid analgesic and antipyretic agent used to treat fever and mild to moderate pain.[13][14][15] It is a widely used over the counter medication. Common brand names include Tylenol and Panadol. At a standard dose, paracetamol only slightly reduces fever;[14][16][17] it is inferior to ibuprofen in that ...
Tramadol, sold under the brand name Ultram among others,[1] is an opioid pain medication and a serotonin–norepinephrine reuptake inhibitor (SNRI) used to treat moderately severe pain.[3][14] When taken by mouth in an immediate-release formulation, the onset of pain relief usually begins within an hour.[3] It is also available by injection ...
- Structure
- Production
- Applications
- Metabolism
- Historical Cases of Contamination with Diethylene Glycol
- Etymology
- See Also
- External Links
Although achiral, glycerol is prochiral with respect to reactions of one of the two primary alcohols. Thus, in substituted derivatives, the stereospecific numbering labels the molecule with a sn- prefix before the stem name of the molecule.
Glycerol is generally obtained from plant and animal sources where it occurs in triglycerides, esters of glycerol with long-chain carboxylic acids. The hydrolysis, saponification, or transesterificationof these triglycerides produces glycerol as well as the fatty acid derivative: Triglycerides can be saponified with sodium hydroxide to give glycero...
Food industry
In food and beverages, glycerol serves as a humectant, solvent, and sweetener, and may help preserve foods. It is also used as filler in commercially prepared low-fat foods (e.g., cookies), and as a thickening agent in liqueurs. Glycerol and water are used to preserve certain types of plant leaves. As a sugar substitute, it has approximately 27 kilocalories per teaspoon (sugar has 20) and is 60% as sweet as sucrose. It does not feed the bacteria that form a dental plaque and cause dental cavi...
Medical, pharmaceutical and personal care applications
Glycerol is used in medical, pharmaceutical and personal care preparations, often as a means of improving smoothness, providing lubrication, and as a humectant. Ichthyosis and xerosis have been relieved by the topical use of glycerin. It is found in allergen immunotherapies, cough syrups, elixirs and expectorants, toothpaste, mouthwashes, skin care products, shaving cream, hair care products, soaps, and water-based personal lubricants. In solid dosage forms like tablets, glycerol is used as a...
Botanical extracts
When utilized in "tincture" method extractions, specifically as a 10% solution, glycerol prevents tannins from precipitating in ethanol extracts of plants (tinctures). It is also used as an "alcohol-free" alternative to ethanol as a solvent in preparing herbal extractions. It is less extractive when utilized in a standard tincture methodology. Alcohol-based tinctures can also have the alcohol removed and replaced with glycerol for its preserving properties. Such products are not "alcohol-free...
Glycerol is a precursor for synthesis of triacylglycerols and of phospholipids in the liver and adipose tissue. When the body uses stored fat as a source of energy, glycerol and fatty acidsare released into the bloodstream. Glycerol is mainly metabolized in the liver. Glycerol injections can be used as a simple test for liver damage, as its rate of...
On 4 May 2007, the FDA advised all U.S. makers of medicines to test all batches of glycerol for diethylene glycol contamination. This followed an occurrence of hundreds of fatal poisonings in Panama resulting from a falsified import customs declaration by Panamanian import/export firm Aduanas Javier de Gracia Express, S. A. The cheaper diethylene g...
The origin of the gly- and glu- prefixes for glycols and sugars is from Ancient Greek γλυκύς glukus which means sweet. Name glycérine was coined ca. 1811 by Michel Eugène Chevreul to denote what was previously called "sweet principle of fat" by its discoverer Carl Wilhelm Scheele. It was borrowed into English ca. 1838 and in the 20th c. displaced b...
Mass spectrum of glycerol Archived 13 February 2022 at the Wayback MachineKetamine is a dissociative anesthetic used medically for induction and maintenance of anesthesia. It is also used as a treatment for depression and pain management.[19] It is a novel compound that was derived from phencyclidine in 1962 in pursuit of a safer anesthetic with fewer hallucinogenic effects.[20][21] At anesthetic doses, ketamine ...
Dengue fever is a mosquito-borne disease caused by dengue virus, prevalent in tropical and subtropical areas. It is frequently asymptomatic; if symptoms appear they typically begin 3 to 14 days after infection. These may include a high fever, headache, vomiting, muscle and joint pains, and a characteristic skin itching and skin rash. Recovery ...
Shingles, also known as herpes zoster, is a viral disease characterized by a painful skin rash with blisters in a localized area. [2] [6] Typically the rash occurs in a single, wide mark either on the left or right side of the body or face. [1] Two to four days before the rash occurs there may be tingling or local pain in the area.
The Cure are an English rock band formed in 1978 in Crawley, West Sussex. [1] [2] [3] Throughout numerous lineup changes since the band's formation, guitarist, lead vocalist, and songwriter Robert Smith has remained the only constant member, though bassist Simon Gallup has been present for all but about three years of the band's history.
