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Vitamin D is a group of fat-soluble secosteroids responsible for increasing intestinal absorption of calcium, magnesium, and phosphate, and for many other biological effects.[1][2][3] In humans, the most important compounds in this group are vitamin D3 (cholecalciferol) and vitamin D2 (ergocalciferol).[2][3][4] The major natural source of ...
The vitamin D receptor ( VDR also known as the calcitriol receptor) is a member of the nuclear receptor family of transcription factors. [5] Calcitriol (the active form of vitamin D, 1,25- (OH) 2 vitamin D 3) binds to VDR, which then forms a heterodimer with the retinoid-X receptor. The VDR heterodimer then enters the nucleus and binds to ...
Cholecalciferol, also known as vitamin D3 and colecalciferol, is a type of vitamin D that is made by the skin when exposed to UV-B light; it is found in some foods and can be taken as a dietary supplement. [3] Cholecalciferol is made in the skin following UVB light exposure. [4] It is converted in the liver to calcifediol (25-hydroxyvitamin D ...
Dopamine receptor D3 is a protein that in humans is encoded by the DRD3 gene.[5][6] This gene encodes the D3 subtype of the dopamine receptor. The D3 subtype inhibits adenylyl cyclase through inhibitory G-proteins. This receptor is expressed in phylogenetically older regions of the brain, suggesting that this receptor plays a role in cognitive ...
Paracetamol (acetaminophen[a]) is a non-opioid analgesic and antipyretic agent used to treat fever and mild to moderate pain.[13][14][15] It is a widely used over the counter medication. Common brand names include Tylenol and Panadol. At a standard dose, paracetamol only slightly reduces fever;[14][16][17] it is inferior to ibuprofen in that ...
Lysergic acid diethylamide, commonly known as LSD (from German Lysergsäure-diethylamid), and known colloquially as acid or lucy, is a potent psychedelic drug.[12] Effects typically include intensified thoughts, emotions, and sensory perception.[13] At sufficiently high dosages, LSD manifests primarily mental, visual, and auditory ...
Diazepam, sold under the brand name Valium among others, is a medicine of the benzodiazepine family that acts as an anxiolytic.[14] It is used to treat a range of conditions, including anxiety, seizures, alcohol withdrawal syndrome, muscle spasms, insomnia, and restless legs syndrome.[14] It may also be used to cause memory loss during certain ...
