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XEN1101 is a novel positive allosteric modulator ("opener") of the potassium channel KCNQ2/3 (Kv7.2/7.3) currently being developed by Xenon Pharmaceuticals Inc. for the treatment of focal epilepsy. Potentiating the open state of KCNQ2/3 channels favors a hyperpolarized resting state. This mechanism has been clinically proven effective for focal ...
Thickened fluids. Thickened fluids and thickened drinks are often used for people with dysphagia, a disorder of swallowing function. [1] The thicker consistency makes it less likely that individuals will aspirate while they are drinking. Individuals with difficulty swallowing may find that liquids cause coughing, spluttering, or even aspiration ...
Gammaproteobacteria is a class of bacteria in the phylum Pseudomonadota (synonym Proteobacteria ). It contains about 250 genera, which makes it the most genus-rich taxon of the Prokaryotes. [1] Several medically, ecologically, and scientifically important groups of bacteria belong to this class. All members of this class are Gram-negative.
El Questro Gorge waterfall. El Questro Wilderness Park is a wilderness park on El Questro Station, a cattle station that diversified its pastoral operation to include tourism, located in the Kimberley region of Western Australia. It remains a working cattle station with a herd of approximately 6,000 head. In 2012 the pastoral station lessee was ...
Lacticaseibacillus paracasei. Lacticaseibacillus paracasei (commonly abbreviated as Lc. paracasei) is a gram-positive, homofermentative species of lactic acid bacteria that are commonly used in dairy product fermentation and as probiotic cultures. Lc. paracasei is a bacterium that operates by commensalism. It is commonly found in many human ...
Translocon-associated protein subunit alpha is a protein that in humans is encoded by the SSR1 gene. [5] The signal sequence receptor (SSR) is a glycosylated endoplasmic reticulum (ER) membrane receptor associated with protein translocation across the ER membrane. The SSR consists of 2 subunits, a 34-kD glycoprotein encoded by this gene and a ...
Rhamphocottus nagaakii. Rhamphocottus nagaakii is a species of marine ray-finned fish belonging to the family Rhamphocottidae, the grunt sculpins. This species was first formally described in 2022 with its type locality given as off Minami-Sanriku cho in Miyagi Prefecture of Japan. [1] It is thought to have evolved from a common ancestor to the ...
