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2017年10月30日 · What is cholesterol? A Plastic in the blood. B A waxy, fatty substance in the blood. C A type of blood cell. D A derivative of salt. The correct answer is: A waxy, fatty substance in the blood. Explanation: Cholesterol is a fatty, waxy substance that is present in every cell of the body and is carried in the bloodstream. next question. 02.
- Mechanism of Action
- Pharmacokinetics
- Special Populations
- Drug Interactions
- Clinical Studies
- Pediatric Patients 6 to 17 Years of Age
Rizatriptan binds with high affinity to human cloned 5-HT1B/1D receptors. MAXALT presumably exerts its therapeutic effects in the treatment of migraine headache by binding to 5-HT1B/1D receptors located on intracranial blood vessels and sensory nerves of the trigeminal system.
Rizatriptan is completely absorbed following oral administration. The mean oral absolute bioavailability of the MAXALT Tablet is about 45%, and mean peak plasma concentrations (Cmax) are reached in approximately 1-1.5 hours (Tmax). The presence of a migraine headache did not appear to affect the absorption or pharmacokinetics of rizatriptan. Food h...
Rizatriptan pharmacokinetics in healthy elderly non-migraineur volunteers (age 65-77 years) were similar to those in younger non-migraineur volunteers (age 18-45 years). The pharmacokinetics of rizatriptan was determined in pediatric migraineurs 6 to 17 years of age. Exposures following single dose administration of 5 mg MAXALT-MLT to pediatric pat...
[See also DRUG INTERACTIONS] Rizatriptan is principally metabolized via monoamine oxidase, ‘A’ subtype (MAO-A). Plasma concentrations of rizatriptan may be increased by drugs that are selective MAO-A inhibitors (e.g., moclobemide) or nonselective MAO inhibitors [type A and B] (e.g., isocarboxazid, phenelzine, tranylcypromine, and pargyline). In...
The efficacy of MAXALT Tablets was established in four multicenter, randomized, placebo-controlled trials. Patients enrolled in these studies were primarily female (84%) and Caucasian (88%), with a mean age of 40 years (range of 18 to 71). Patients were instructed to treat a moderate to severe headache. Headache response, defined as a reduction of ...
The efficacy of MAXALT-MLT in pediatric patients 6 to 17 years was evaluated in a multicenter, randomized, double-blind, placebo-controlled, parallel group clinical trial (Study 7). Patients had to have at least a 6-month history of migraine attacks (with or without aura) usually lasting 3 hours or more (when untreated). The patient population was ...
2023年10月30日 · Panhematin (hemin for injection) is an enzyme inhibitor that is made from red blood cells that acts as a mild anticoagulant used to treat the symptoms of occasional attacks of porphyria related to the menstrual cycle in women. Panhematin helps control symptoms such as pain, increased heart rate or blood pressure, and changes in mental status.
2022年7月29日 · What are the most common blood pressure medications? In terms of dollar sales, there are 5 top high blood pressure medications. the angiotensin II receptor blocker valsartan (Diovan) in the lead for high blood pressure medications, the beta-blocker metoprolol, the generic combination of valsartan and HCTZ, olmesartan (Benicar), and.
2023年6月6日 · What Is Cozaar? Cozaar (losartan) is an oral angiotensin receptor blocker (ARB) prescribed for the treatment of hypertension. What Are Side Effects of Cozaar? Side effects of Cozaar include: diarrhea. stomach pain. muscle cramps. leg or back pain. dizziness. headache. sleep problems (insomnia) tiredness, and.
Gower syndrome is caused by a reflex of the involuntary nervous system called the vasovagal reaction. The vasovagal reaction leads the heart to slow down ( bradycardia) and, at the same time, it leads the nerves to the blood vessels in the legs to permit those vessels to dilate (widen).
Hypercholesterolemia is one form of hyperlipidemia. Familial hypercholesterolemia is the most common inherited type of hyperlipidemia (high fat or lipid levels in blood). It predisposes to premature arteriosclerosis including coronary artery disease with heart attacks at an unusually young age.
