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1. www.rxlist.com › zovirax-drugZovirax (Acyclovir): Side Effects, Uses, Dosage, ...

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   Accidental, repeated overdoses of oral acyclovir over several days have been associated with gastrointestinal effects (such as nausea and vomiting) and neurological effects (headache and confusion). Intravenous doses administered to humans have been as high as 1,200 mg/m² (28 mg/kg) 3 times daily for up to 2 weeks.

2. www.rxlist.comRxList - The Internet Drug Index for prescription drug ...

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   Medications and prescription drug information for consumers and medical health professionals. Online database of the most popular drugs and their side effects, interactions, and use. Featured Centers What Are the Best PsA Treatments for You? Understanding

3. www.rxlist.com › norvasc-drugNorvasc (Amlodipine Besylate): Side Effects, Uses, Dosage, ...

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   • Mechanism of Action
   • Pharmacodynamics
   • Drug Interactions
   • Pharmacokinetics
   • Pediatric Patients
   • Effects in Hypertension
   • Effects in Chronic Stable Angina
   • Effects in Vasospastic Angina
   • Effects in Documented Coronary Artery Disease
   • Studies in Patients with Heart Failure

   Amlodipine is a dihydropyridine calcium antagonist (calcium ion antagonist or slow-channel blocker) that inhibits the transmembrane influx of calcium ions into vascular smooth muscle and cardiac muscle. Experimental data suggest that amlodipine binds to both dihydropyridine and nondihydropyridine binding sites. The contractile processes of cardiac ...

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   Following administration of therapeutic doses to patients with hypertension, NORVASC produces vasodilation resulting in a reduction of supine and standing blood pressures. These decreases in blood pressure are not accompanied by a significant change in heart rate or plasma catecholamine levels with chronic dosing. Although the acute intravenous adm...

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   When amlodipine and sildenafil were used in combination, each agent independently exerted its own blood pressure lowering effect [see DRUG INTERACTIONS].

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   After oral administration of therapeutic doses of NORVASC, absorption produces peak plasma concentrations between 6 and 12 hours. Absolute bioavailability has been estimated to be between 64 and 90%. The bioavailability of NORVASC is not altered by the presence of food. Amlodipine is extensively (about 90%) converted to inactive metabolites via hep...

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   Sixty-two hypertensive patients aged 6 to 17 years received doses of NORVASC between 1.25 mg and 20 mg. Weight-adjusted clearance and volume of distribution were similar to values in adults.

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   The antihypertensive efficacy of NORVASC has been demonstrated in a total of 15 double-blind, placebo-controlled, randomized studies involving 800 patients on NORVASC and 538 on placebo. Once daily administration produced statistically significant placebo-corrected reductions in supine and standing blood pressures at 24 hours postdose, averaging ab...

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   The effectiveness of 5-10 mg/day of NORVASC in exercise-induced angina has been evaluated in 8 placebo-controlled, double-blind clinical trials of up to 6 weeks duration involving 1038 patients (684 NORVASC, 354 placebo) with chronic stable angina. In 5 of the 8 studies, significant increases in exercise time (bicycle or treadmill) were seen with t...

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   In a double-blind, placebo-controlled clinical trial of 4 weeks duration in 50 patients, NORVASC therapy decreased attacks by approximately 4/week compared with a placebo decrease of approximately 1/week (p<0.01). Two of 23 NORVASC and 7 of 27 placebo patients discontinued from the study due to lack of clinical improvement.

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   In PREVENT, 825 patients with angiographically documented coronary artery disease were randomized to NORVASC (5-10 mg once daily) or placebo and followed for 3 years. Although the study did not show significance on the primary objective of change in coronary luminal diameter as assessed by quantitative coronary angiography, the data suggested a fav...

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   NORVASC has been compared to placebo in four 8-12 week studies of patients with NYHA Class II/III heart failure, involving a total of 697 patients. In these studies, there was no evidence of worsened heart failure based on measures of exercise tolerance, NYHA classification, symptoms, or left ventricular ejection fraction. In a long-term (follow-up...

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4. www.rxlist.com › lyrica-drugLyrica (Pregabalin): Side Effects, Uses, Dosage, ...

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   2024年1月8日 · The recommended dose range of LYRICA for the treatment of neuropathic pain associated with spinal cord injury is 150 to 600 mg/day. The recommended starting dose is 75 mg two times a day (150 mg/day). The dose may be increased to 150 mg two times a day (300 mg/day) within 1 week based on efficacy and tolerability.

5. www.rxlist.com › eliquis-drugEliquis (Apixaban Tablets): Side Effects, Uses, Dosage, ...

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   2022年3月7日 · The most common side effects of Eliquis are related to bleeding. Other side effects of Eliquis include: skin rash, allergic reactions, fainting, nausea, and. anemia. Tell your doctor if you have serious side effects of Eliquis including easy: bruising, unusual bleeding (nose, mouth, vagina, or rectum ),

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6. www.rxlist.com › myrbetriq-drugMyrbetriq (Mirabegron): Side Effects, Uses, Dosage, ...

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   2022年10月25日 · What Is Myrbetriq? Myrbetriq (mirabegron) is a beta-3 adrenergic agonist used to treat overactive bladder (OAB) with symptoms of urge urinary incontinence, urgency, and urinary frequency. What Are Side Effects of Myrbetriq? Myrbetriq may cause serious side effects including: fast or pounding heartbeats, pain or burning when you urinate,

7. www.rxlist.com › augmentin-drugAugmentin (Amoxicillin Clavulanate): Side Effects, Uses, ...

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   2023年9月7日 · Adults. The usual adult dose is one 500-mg tablet of AUGMENTIN every 12 hours or one 250-mg tablet of AUGMENTIN every 8 hours. For more severe infections and infections of the respiratory tract, the dose should be one 875-mg tablet of AUGMENTIN every 12 hours or one 500-mg tablet of AUGMENTIN every 8 hours.