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Owing to the extremely efficient enterohepatic circulation of B 12, the liver can store 3 to 5 years' worth of vitamin B 12; therefore, nutritional deficiency of this vitamin is rare in adults in the absence of malabsorption disorders. [12]
Poor vitamin B status has been shown to be associated with an increased risk of frailty. Two cross sectional studies have reported that deficiencies of vitamin B 12 were associated with the length of hospital stay, as observed by serum vitamin B 12 [102]
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What is a normal vitamin B 12 level?
How much vitamin B 12 is stored in the body?
How is B12 absorbed in the body?
How does vitamin B12 affect a person's health?
Hydroxocobalamin, also known as vitamin B 12a and hydroxycobalamin, is a vitamin found in food and used as a dietary supplement. [1] As a supplement it is used to treat vitamin B12 deficiency including pernicious anemia .
Although the healthy body stores three to five years' worth of B 12 in the liver, the usually undetected autoimmune activity in one's gut over a prolonged period of time leads to B 12 depletion and the resulting anemia; pernicious anemia refers to one of the 12.
Adenosylcobalamin (AdoCbl), also known as coenzyme B12, cobamamide, and dibencozide, is, along with methylcobalamin (MeCbl), one of the biologically active forms of vitamin B 12. [ 1] Adenosylcobalamin participates as a cofactor in radical-mediated 1,2-carbon skeleton rearrangements.
It is also used to treat pernicious anemia, vitamin B 12 deficiency (due to low intake from food or inability to absorb due to genetic or other factors), thyrotoxicosis, hemorrhage, malignancy, liver disease and kidney disease.
Normal total body vitamin B 12 is between 2 and 5 mg with 50% of that stored in the liver. Total serum vitamin B 12 may not be a reliable biomarker for reflecting what the body stores inside cells. Vitamin B 12 levels can be falsely high or low and data for
How long does vitamin B12 stay in the liver? 相關
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