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This Viewpoint describes how to interpret 2 types of diagnostic tests commonly in use for SARS-CoV-2 infections—reverse transcriptase–polymerase chain reaction (RT-PCR) and IgM and IgG enzyme-linked immunosorbent assay (ELISA)—and how the results).
- Nandini Sethuraman, Sundararaj Stanleyraj Jeremiah, Akihide Ryo
- 2020
Serum IgM anti-PSPT antibody levels could be related to the common pathogenic factors that trigger the development of severe HSP, gastrointestinal symptoms, and HSP nephritis. As such, the IgM-antigen complex, as a heavy molecule, could be preferentially trapped in the capillaries of kidney and the digestive tract.
- Tamihiro Kawakami, Sora Takeuchi, Yoshinao Soma
- 2011
2018年11月2日 · Monitoring of immunoglobulin levels both before and after rituximab therapy may allow for earlier identification of risk for developing significant infection and identify patients who may benefit from immunoglobulin replacement, which may in turn help to avoid excess
- Sara Barmettler, Mei-Sing Ong, Jocelyn R. Farmer, Hyon Choi, Jolan Walter, Jolan Walter
- 2018
Key Points Question Do corticosteroids safely prevent loss of kidney function in patients with IgA nephropathy receiving optimal supportive therapy? Findings This randomized clinical trial that included 262 participants was stopped early (after 28 of the 335 planned events) due to a significantly increased risk of serious adverse events with oral methylprednisolone vs placebo (14.7% vs 3.2% ...
After the patient did not respond to rituximab, intravenous immunoglobulin, and cyclophosphamide, a second biopsy specimen was obtained for direct immunofluorescence. The results demonstrated deposition of linear IgA, sparse granular C3, but no IgG along
2023年2月6日 · The Effect of Mycophenolate Mofetil on Renal Outcomes in Advanced Immunoglobulin A Nephropathy (MAIN) was a prospective, open-label, RCT with a blinded end point conducted at the Renal Division of Nanfang Hospital, a center for kidney disease care in
2023年7月31日 · While it may be reasonable to use an Ig G titer cutoff of at least 1:800 as diagnostic evidence of Bartonella IE, clinicians should be aware that the data set supporting accuracy of this cutoff is limited, 22 patients who do not have IE can have titers as high as 1: