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  1. 2018年6月5日 · Explanation of the Concept. What Are Permuted Blocks and Stratified Randomization? The permuted block technique randomizes patients between groups within a set of study participants, called a block.

    • Kristine Broglio
    • 2018
  2. 2000年4月19日 · Because of pressure for timely and informed decisions in public health and medicine and the explosion of information in the scientific literature, research results must be synthesized to answer urgent questions. 1-4 Principles of evidence-based methods to assess the effectiveness of health care interventions and set policy are cited increasingly. 5 Meta-analysis, a systematic approach to ...

    • D F Stroup, J A Berlin, S C Morton, I Olkin, G D Williamson, D Rennie, D Rennie, D Moher, B J Becker...
    • 2000
  3. Full. Abstract. ImportanceCaregiver burden may result from providing care for patients with chronic illness. It can occur in any of the 43.5 million individuals providing support to midlife and older adults. Caregiver burden is frequently overlooked by clinicians. ObjectivesTo outline the epidemiology of caregiver burden; to provide strategies ...

  4. Importance Mendelian randomization (MR) studies use genetic variation associated with modifiable exposures to assess their possible causal relationship with outcomes and aim to reduce potential bias from confounding and reverse causation. Objective To develop the STROBE-MR Statement as a stand-alone extension to the STROBE (Strengthening the Reporting of Observational Studies in Epidemiology ...

  5. Importance Functional decline is prevalent among acutely hospitalized older patients. Exercise and early rehabilitation protocols applied during acute hospitalization can prevent functional and cognitive decline in older patients. Objective To assess the effects of an innovative multicomponent exercise intervention on the functional status of this patient population.

  6. Such studies may be subject to immortal time bias, meaning that, during the period of observation, there is some interval during which the outcome event cannot occur. The research participants are “immortal” in that they must survive long enough to receive the intervention being studied.

  7. Myopia has reached epidemic levels in young adults in some urban areas of East and Southeast Asia. 1 In these areas, 80% to 90% of high school graduates now have myopia and approximately 20% have high myopia (defined as ≤−6 diopters [D]). 2 Myopia also appears to be increasing, albeit more slowly, in populations of European and Middle Eastern origin. 3,4 The increasing prevalence of myopia ...

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