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2022年8月28日 · Tricompartmental osteoarthritis is a type of arthritis that affects your knee. In osteoarthritis, or OA, the smooth, slippery cartilage that covers the ends of your bones and helps them glide...
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No matter which osteoporosis drug your doctor chooses for you, it's helpful to know as much as possible about how the disease has affected you. One way to tell is to ask about your \"markers.\"
What a difference a decade makes. In 1995, Fosamax, the first medication in a class of drugs called bisphosphonates, came on the market.
Bisphosphonates affect what's called the bone remodeling cycle, which involves bone resorption (the dissolving of existing bone tissue) and formation (the filling of the resulting small cavities with new bone tissue). Usually, these two parts of the cycle are balanced, but when resorption outpaces formation, you eventually have osteoporosis.
By slowing or stopping the bone-resorbing portion of the remodeling cycle, bisphosphonates allow new bone formation to catch up with bone resorption. Fosamax and other drugs such as Actonel, Boniva, and Reclast increase bone density and help prevent and treat osteoporosis and/or reduce the risk of fractures.
\"Over three years on Fosamax, you can expect a 6% to 8% increase in spinal bone density and a 4% to 6% increase in hip bone density,\" says Michael Holick, MD, PhD, a professor of medicine, physiology, and biophysics at Boston University Medical Center. \"And the bisphosphonates have been found to reduce spinal fracture by as much as 60% over thre...
Recently completed studies show that these effects continue with long-term use. \"You see the most dramatic effect in the first three to five years on the medications, but we continue to see a smaller but significant increase in bone density for up to 10 years,\" Holick says. \"More important, if you stop taking the drugs, you begin to lose bone at...
But bisphosphonates do have some limitations. For one thing, the regimen for taking them effectively is very intense. Sinceas little as 1%- 5 % of the drug is absorbed by your body -- the rest is excreted -- you have to make sure to make the most of every dose. With drugs like Fosamax and Actonel, this means taking it first thing in the morning onc...
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2024年2月11日 · The Fracture Risk Assessment Tool, or FRAX, is a free online tool that estimates your risk of having a hip or other major fracture in the next 10 years, especially if you have osteoporosis....
2022年8月28日 · What Is Subchondral Sclerosis? Subchondral sclerosis is a thickening of bone that happens in joints affected by osteoarthritis. If you’ve been diagnosed with osteoarthritis or have early symptoms...
Empty nose syndrome is a rare complication of nasal surgery. It can make it hard for you to breathe properly, and it can cause headaches and nosebleeds. Household Pests: Moths. Moths sometimes ...
2024年3月20日 · What Is Appendicitis? Appendicitis is an inflammation of the appendix. It's a medical emergency that almost always requires surgery as soon as possible to remove the appendix. Luckily, you can...
