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The vitamin D receptor ( VDR also known as the calcitriol receptor) is a member of the nuclear receptor family of transcription factors. [5] Calcitriol (the active form of vitamin D, 1,25- (OH) 2 vitamin D 3) binds to VDR, which then forms a heterodimer with the retinoid-X receptor. The VDR heterodimer then enters the nucleus and binds to ...
Vitamin D is a group of fat-soluble secosteroids responsible for increasing intestinal absorption of calcium, magnesium, and phosphate, and for many other biological effects.[1][2][3] In humans, the most important compounds in this group are vitamin D3 (cholecalciferol) and vitamin D2 (ergocalciferol).[2][3][4] The major natural source of ...
Ergocalciferol is a secosteroid formed by a photochemical bond breaking of a steroid, specifically, by the action of ultraviolet light (UV-B or UV-C) on ergosterol, a form of provitamin D 2. [19] Like cholecalciferol, ergocalciferol is inactive by itself. It requires two hydroxylations to become active: the first in the liver by CYP2R1 to form ...
Dwayne Douglas Johnson (born May 2, 1972), also known by his ring name The Rock, is an American actor, businessman, and professional wrestler. As a wrestler, he is signed to WWE, where he performs on a part-time basis and is a member of The Bloodline. Widely regarded as one of the greatest professional wrestlers of all time,[6][7] he was ...
Andrew David Huberman (born September 26, 1975) is an American neuroscientist and podcaster.He is an associate professor of neurobiology and ophthalmology at the Stanford University School of Medicine.Since 2021, he has hosted the Huberman Lab podcast, which despite its popularity has attracted criticism for promoting poorly supported health claims.
JoJo Siwa. Joelle Joanie " JoJo " Siwa ( / ˈsiːwɑː /; born May 19, 2003) is an American singer, dancer, actress, and media personality. From 2015 to 2016, she appeared as a dancer on two seasons of the reality television show Dance Moms alongside her mother, Jessalynn Siwa. In 2017, Siwa signed to Nickelodeon and acted in various shows and ...
Sir David Frederick Attenborough (/ ˈ æ t ən b ə r ə /; born 8 May 1926) is a British broadcaster, biologist, natural historian, and writer.He is best known for writing and presenting, in conjunction with the BBC Natural History Unit, the nine natural history documentary series forming the Life collection, a comprehensive survey of animal and plant life on Earth.
