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  1. Parkinson's disease ( PD ), or simply Parkinson's, is a long-term neurodegenerative disease of mainly the central nervous system that affects both the motor system and non-motor systems. The symptoms usually emerge slowly, and as the disease progresses, non-motor symptoms become more common. Usual symptoms are tremor, slowness of movement ...

  2. en.wikipedia.org › wiki › ParkinsonismParkinsonism - Wikipedia

    Parkinsonism is a clinical syndrome characterized by tremor, bradykinesia (slowed movements), rigidity, and postural instability. [1] [2] Both hypokinetic (bradykinesia and akinesia) as well as hyperkinetic (cogwheel rigidity and tremors at rest) features are displayed by Parkinsonism. [3] These are the four motor symptoms found in Parkinson's ...

  3. Alzheimer's disease ( AD) is a neurodegenerative disease that usually starts slowly and progressively worsens, [2] and is the cause of 60–70% of cases of dementia. [2] [15] The most common early symptom is difficulty in remembering recent events. [1] As the disease advances, symptoms can include problems with language, disorientation ...

  4. en.wikipedia.org › wiki › ALSALS - Wikipedia

    Amyotrophic lateral sclerosis (ALS), also known as motor neurone disease (MND) or Lou Gehrig's disease in the United States, is a rare but terminal neurodegenerative disorder that results in the progressive loss of both upper and lower motor neurons that normally control voluntary muscle contraction.[3] ALS is the most common form of the motor ...

  5. Schizophrenia is a mental disorder[17] characterized by reoccurring episodes of psychosis that are correlated with a general misperception of reality.[7] Other common signs include hallucinations (typically hearing voices), delusions (i.e., paranoia), disorganized thinking and behavior,[10] social withdrawal, and flat affect.[7] Symptoms ...

  6. Down syndrome or Down's syndrome, also known as trisomy 21, is a genetic disorder caused by the presence of all or part of a third copy of chromosome 21. [3] It is usually associated with developmental delays, mild to moderate intellectual disability, and characteristic physical features. [1] [12] There are three types of Down syndrome, the ...

  7. Huntington's disease (HD), also known as Huntington's chorea, is an incurable neurodegenerative disease[7] that is mostly inherited.[8] The earliest symptoms are often subtle problems with mood or mental/psychiatric abilities.[9][1] A general lack of coordination and an unsteady gait often follow.[2] It is also a basal ganglia disease causing ...

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