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Other causes of B12 malabsorption include intrinsic factor deficiency, pernicious anemia, bariatric surgery pancreatic insufficiency, obstructive jaundice, tropical sprue and celiac disease, and radiation enteritis of the distal ileum.
Vitamin B 12 deficiency. Appearance. hide. Vitamin B12 deficiency, also known as cobalamin deficiency, is the medical condition in which the blood and tissue have a lower than normal level of vitamin B 12. [5] . Symptoms can vary from none to severe. [1] . Mild deficiency may have few or absent symptoms. [1] .
Side effects. Possible side effects of cyanocobalamin injection include allergic reactions such as hives, difficult breathing; redness of the face; swelling of the arms, hands, feet, ankles or lower legs; extreme thirst; and diarrhea. Less-serious side effects may include headache, dizziness, leg pain, itching, or rash. [18]
Serum vitamin B12 is a medical laboratory test that measure vitamin B 12 only in the blood binding to both transcobalamins. [1] . Most of the time, 80–94% of vitamin B 12 in the blood binds to haptocorrin, while only 6–20% is binds to transcobalamin ll. [2] Only transcobalamin ll is "active" and can be used by the body. [1] .
In molecular biology, the vitamin B12-binding domain is a protein domain which binds to cobalamin (vitamin B12). It can bind two different forms of the cobalamin cofactor, with cobalt bonded either to a methyl group (methylcobalamin) or to 5'-deoxyadenosine (adenosylcobalamin).
Vitamin B12 deficiency Vitamin B12 total synthesis This page was last edited on 7 September 2019, at 03:49 (UTC). Text is available under the Creative Commons Attribution-ShareAlike License 4.0; additional terms may apply. By using this site, you agree to ...
Ethylenediaminetetraacetic acid ( EDTA ), also called EDTA acid after its own abbreviation, is an aminopolycarboxylic acid with the formula [CH 2 N (CH 2 CO 2 H) 2] 2. This white, water-insoluble solid is widely used to bind to iron (Fe 2+ /Fe 3+) and calcium ions (Ca 2+ ), forming water-soluble complexes even at neutral pH.
