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2017年6月26日 · AT III是一個強力的凝固抑制因子，是維持凝血生理的重要抗凝劑，當其濃度下降時，可能會造成栓塞和對Heparin治療無效的影響。 AT III除了可以抑制thrombin的活性外，還可以抑制絲氨酸蛋白酶(如：Factor XII、XI、IX、X及II)，其中以抑制thrombin和Factor X活性 ...
2024年3月6日 · Deficiency of antithrombin (AT; antithrombin III) can be inherited or acquired; it is defined as an AT activity level that is consistently less than 80 percent of normal (or the lower limit of the assay's reference range). In some patients, AT deficiency can be associated with an increased risk of thromboembolism.
2023年9月4日 · Biochemistry, Antithrombin III. Eric Hsu; Leila Moosavi. Author Information and Affiliations. Last Update: September 4, 2023. Introduction. Antithrombin is a plasma glycoprotein consisting of 432 amino acid residues integral in the regulation of the coagulation process during bleeding.
Antithrombin III is a vitamin K-dependent serine protease inhibitor that irreversibly inactivates factors XIIa, XIa, IXa, Xa, and IIa (thrombin), all serine proteases. Heparins bind to antithrombin III, enhancing its natural anticoagulant effects.
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2016年2月9日 · Antithrombin III (AT III) is primarily a potent anticoagulant with independent anti-inflammatory properties. AT III irreversibly inhibits serine proteases (e.g. activated factor X and thrombin) in a one-to-one ratio, with the generation of protease–AT III complexes.
2020年8月11日 · Antithrombin (AT, also called AT III) is a serine protease inhibitor of the serpin superfamily that regulates the proteolytic activity of procoagulant proteases of both intrinsic and extrinsic pathways. 1-4 It is synthesized in the liver as a single-chain glycoprotein with 5
2015年3月21日 · Antithrombin III (ATIII) is a nonvitamin K-dependent protease that inhibits coagulation by lysing thrombin and factor Xa. Antithrombin III activity is markedly potentiated by heparin,...
抗凝血酵素III是一種絲氨酸蛋白酵素的抑制劑，它可 以藉由抑制凝血酵素(thrombin)和凝血因子IXa、Xa、 XIa、XIIa，胞漿素(plasmin)，和卡力克連 (kallikreihn)來保護身體對抗血栓的形成，它負責人類 血漿中70-90%的抗凝血活性，它的活性可以被肝素增強 100倍。
antithrombin III是一種蛋白質，可抑制thrombin、第十與第九凝血因子之活性。 若有antithrombin III之缺陷，臨床上可能有嚴重之血栓。 此檢驗是檢測anti-thrombin III之功能。
臨床意義 or 實驗室解釋：antithrombin III是一種蛋白質，可抑制thrombin、第十與第九凝血因子之活性。 若有antithrombin III之缺陷，臨床上可能有嚴重之血栓。 此檢驗是檢測anti-thrombin III之功能。 是否接受院外委託檢驗：否. 回上一頁. 回最上面. 回首頁.
