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  1. 2021年3月5日 · CAR T cells specific for CD66c, CD318 and TSPAN8 demonstrate efficacies ranging from stabilized disease to complete tumor eradication with CD318 followed by TSPAN8 being the most promising ...

    • Daniel Schäfer, Daniel Schäfer, Stefan Tomiuk, Laura N. Küster, Wa’el Al Rawashdeh, Janina Henze, Ja...
    • 2021
  2. 2021年3月11日 · 在CD66c、CD318和TSPAN8特异性的CAR-T细胞中,CD318表现出了从疾病稳定到彻底根除肿瘤的功效,其次是TSPAN8,基于功能性和预测的安全性,其是最有希望的潜在的候选靶标。

  3. 2021年4月29日 · 在一项新的研究中,德国研究人员进行了经验性筛选旨在发现治疗PDAC的CAR候选靶标,确定了四个候选靶标:CLA、TSPAN8、CD66c和CD318。 他们发现CLA在上皮性肿瘤上表达。

  4. en.wikipedia.org › wiki › CDCP1CDCP1 - Wikipedia

    [5] [6] CDCP1 has also been designated as CD318 (cluster of differentiation 318) and Trask (Transmembrane and associated with src kinases). Alternatively spliced transcript variants encoding distinct isoforms have been reported.

  5. 2017年8月8日 · CD318 is a potential biomarker for inflammatory arthritis and chemotactic for T cells. (A) CD318 is highly expressed in synovial tissues from RA patients.

    • Gospel Enyindah-Asonye, Yan Li, Jeffrey H. Ruth, Danislav S. Spassov, Katie E. Hebron, Andries Zijls...
    • 10.1073/pnas.1704008114
    • 2017
    • 2017/08/08
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  7. 2017年8月15日 · We have identified this CD6 ligand as CD318, a cell surface protein previously found to be present on various epithelial cells and many tumor cells. We found that, like CD6 knockout (KO) mice, CD318 KO mice are also protected in experimental autoimmune encephalomyelitis.

  8. 2021年3月5日 · We identified four target candidates, CLA, CD66c, CD318, and TSPAN8, for a possible cellular immunotherapy of PDAC by CAR T cells. CARs specific for CD66c, CD318, and TSPAN8 showed functionality in vitro and in vivo, with CD318 being the most favorable

  1. cd318 相關

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