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  1. 2021年1月2日 · Introduction. Continuous renal replacement therapy (CRRT) delivers gradual clearance of solutes, fluid balance control, and haemodynamic stability. CRRT does not appear to increase survival compared to intermittent renal replacement therapy (IRRT), but may affect renal recovery [1, 2]. Here, we describe how we prescribe CRRT (Fig. 1).

  2. 2012年10月24日 · Introduction Among critically ill patients with acute kidney injury (AKI) needing continuous renal replacement therapy (CRRT), the effect of convective (via continuous venovenous hemofiltration [CVVH]) versus diffusive (via continuous venovenous hemodialysis [CVVHD]) solute clearance on clinical outcomes is unclear. Our objective was to evaluate the feasibility of comparing these two modes in ...

  3. 2020年11月11日 · Background Myoglobin clearance in acute kidney injury requiring renal replacement therapy is important because myoglobin has direct renal toxic effects. Clinical data comparing different modalities of renal replacement therapy addressing myoglobin clearance are limited. This study aimed to compare two renal replacement modalities regarding myoglobin clearance. Methods In this prospective ...

  4. 2023年7月9日 · Furthermore, the oXiris-CVVH group's vasoactive inotropic score (VIS) was significantly lower than the control group in three studies [17, 24, 25]. Two of the included studies showed that the lower serum endotoxin degree was significantly associated with the oXiris filter group after treatment compared to other filters in CRRT [ 6 , 27 ].

  5. 2013年9月19日 · Introduction The primary aim of this study was to determine whether hypophosphatemia during continuous veno-venous hemofiltration (CVVH) is associated with the global outcome of critically ill patients with acute kidney injury (AKI). Methods 760 patients diagnosed with AKI and had received CVVH therapy were retrospectively recruited. Death during the 28-day period and survival at 28 days after ...

  6. 2022年3月22日 · Limited available evidence (n = 77 in total) shows that CVVHD or CVVHDF might prolong filter life compared with CVVH [18, 19]. However, a single-center observational study published in 2021 (n = 284) reported no difference in filter life between CVVHD and CVVHDF (median, 16.4 h vs. 16.8 h) [20]. When CVVH or CVVHDF is used, replacement fluid ...

  7. 2006年10月27日 · Introduction The mechanism of coagulation activation during continuous venovenous hemofiltration (CVVH) has not yet been elucidated. Insight into the mechanism(s) of hemostatic activation within the extracorporeal circuit could result in a more rational approach to anticoagulation. The aim of the present study was to investigate whether CVVH using cellulose triacetate filters causes activation ...

  8. 2006年4月28日 · Introduction The best modality, for continuous renal replacement therapy (CRRT) is currently uncertain and it is poorly understood how transport of different solutes, whether convective or diffusive, changes over time. Methods We conducted a prospective cross over study in a cohort of critically ill patients, comparing small (urea and creatinine) and middle (β2 microglobulin) molecular weight ...

  9. 2012年11月5日 · Achieving the same survival at 90 days, SLED also showed a tendency towards shorter ICU stays and less ventilation days at significantly lower costs than CVVH. The study has several implications, however. First, in terms of outcome and cardiovascular stability, SLED and CVVH appear to be quite equivalent.

  10. 2010年5月27日 · If CVVH is needed, the Na + concentration in the replacement fluid (usually 140 mmol/l) needs to be adjusted in order to avoid rapid changes of the serum Na + concentration. In the present paper we provide some guidance on how to make these adjustments for CVVH. The same principle could be applied for continuous haemo dialysis or diafiltration.

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