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Phenoxybenzamine is used as an anti-hypertensive due to its efficacy in reducing the vasoconstriction caused by epinephrine (adrenaline) and norepinephrine. Phenoxybenzamine forms a permanent covalent bond with adrenergic receptors.
PHENOXYBENZAMINE (PHENOXYBENZAMINE HCL)的用量、作用機轉、副作用、懷孕及哺乳用藥與藥物交互作用，PHENOXYBENZAMINE (PHENOXYBENZAMINE HCL)適應症:周邊循環障礙、雷諾氏病、凍瘡、手足發紺、慢性肢端潰瘍、糖尿病性壞疽。
苯氧苯胺明(Phenoxybenzamine)透過α腎上腺素(Adrenaline)感受器阻斷作用和兒茶酚胺降解來降低血壓，主要用於治療高血壓。 在服用過程中需監測多種系統的副作用，並注意其禁忌人群包括兒童、妊娠期或哺乳期婦女、高血壓患者、哮喘病史者以及對該藥物過敏者。
Phenoxybenzamine (POB) 是具有較長半衰期的非選擇性不可逆的α-blocker，除了阻斷α1受體，也阻斷α2受體，引起神經末梢釋放正腎上腺素，因而刺激心臟的β1受體，引起心跳加快，所以 POB 雖然減少血壓升高風險，但也可能引起心跳過快。
2005年6月13日 · Phenoxybenzamine may decrease the antihypertensive activities of Valsartan. Vardenafil The risk or severity of hypotension and syncope can be increased when Vardenafil is combined with Phenoxybenzamine.
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2023年6月24日 · Phenoxybenzamine is a medication used in the management and treatment of paroxysmal hypertension and sweating resulting from pheochromocytoma. It is in the nonselective, irreversible antagonist of the alpha-adrenergic receptors class of drugs.
Phenoxybenzamine Hydrochloride Capsules 本品所含苯氧苄胺鹽酸鹽（ C 18H 22ClNO．HCl）應為標誌含量之 90.0～110.0%。 鑑別： (1) 按含量測定項操作所得紫外光吸收光譜，檢品溶液與標準品溶液 苯氧苄胺波峰於相同波長處呈最大與最小吸收。 (2)
phenoxybenzamine 相關
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