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2024年9月23日 · Screening. Systematic perturbation of amino acids at endogenous loci provides diverse insights into protein function. Here, we performed a genome-wide screen to globally assess the cell fitness ...
2016年9月16日 · Serine is used for many biosynthetic pathways, including the one-carbon cycle that supports nucleotide synthesis, methylation reactions and antioxidant defence. Although one-carbon metabolism ...
2024年7月1日 · Serine is important in DNA copying and cancer cell growth as it helps produce antioxidants and other substances. This detailed review explores the role of 3-phosphoglycerate dehydrogenase, an ...
2024年7月9日 · D-serine, D/Total serine and glycine/L-serine ratios positively correlated with age in both sexes, while L-serine selectively decreased with older age only in males (Suppl. Table N).
2023年6月22日 · NAL1 is a breeding-valuable pleiotropic gene in rice. This study identifies NAL1 as a bona fide serine protease which degrades OsTPR2, thus modulating the expression of downstream genes related to ...
2024年6月5日 · How serine synthesis is regulated in cancer remains to be further explored. Here the authors identify FBXO7, an E3 ubiquitin ligase, inhibits serine synthesis in hepatocellular carcinoma by ...
2024年1月10日 · Stegen et al. show that serine metabolism is transiently upregulated during osteoclastogenesis, and it drives osteoclast differentiation via epigenetic regulation of NFATc1 expression.
2024年4月1日 · a, Chemical synthesis of serine conjugate with butyrate (SerBut).TFA, trifluoroacetic acid. RT, room temperature. b, Whole cell lysates of Raw 264.7 macrophages stimulated with the indicated ...
2023年1月11日 · Abstract. Protein phosphorylation is one of the most widespread post-translational modifications in biology 1, 2. With advances in mass-spectrometry-based phosphoproteomics, 90,000 sites of serine ...
2024年5月28日 · Hypoxia induces d-serine production by Mycobacterium tuberculosis which inhibits mTORC1 and T-bet expression to restrict downstream CD8+ T cell immune responses and macrophage activation, and ...
serine 相關
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