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1. • • We have identified this CD6 ligand as CD318, a cell surface protein previously found to be present on various epithelial cells and many tumor cells. We found that, like CD6 knockout (KO) mice, CD318 KO mice are also protected in experimental autoimmune encephalomyelitis.
     pubmed.ncbi.nlm.nih.gov/28760953/

     CD318 is a ligand for CD6 - PubMed

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   Is CD318 a ligand for autoimmune encephalomyelitis?

   • We have identified this CD6 ligand as CD318, a cell surface protein previously found to be present on various epithelial cells and many tumor cells. We found that, like CD6 knockout (KO) mice, CD318 KO mice are also protected in experimental autoimmune encephalomyelitis.

   CD318 is a ligand for CD6 - PubMed

   pubmed.ncbi.nlm.nih.gov/28760953/

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   Is CD318 a ligand of CD6?

   • These results establish CD318 as a ligand of CD6 and a potential target for the diagnosis and treatment of autoimmune diseases such as multiple sclerosis and inflammatory arthritis. Keywords: CD318; CD6; T cell; autoimmunity; ligand.

   CD318 is a ligand for CD6 - PubMed

   pubmed.ncbi.nlm.nih.gov/28760953/

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   Are CD318 KO mice protected in experimental autoimmune encephalomyelitis?

   • We found that, like CD6 knockout (KO) mice, CD318 KO mice are also protected in experimental autoimmune encephalomyelitis. In humans, we found that CD318 is highly expressed in synovial tissues and participates in CD6-dependent adhesion of T cells to synovial fibroblasts.

   CD318 is a ligand for CD6 - PubMed

   pubmed.ncbi.nlm.nih.gov/28760953/

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   Is Mab 3a11 a new CD6 ligand?

   • The antigen recognized by mAb 3A11 has been proposed as a new CD6 ligand distinct from CD166, yet the identity of it is hitherto unknown. We have identified this CD6 ligand as CD318, a cell surface protein previously found to be present on various epithelial cells and many tumor cells.

   CD318 is a ligand for CD6 - PubMed

   pubmed.ncbi.nlm.nih.gov/28760953/

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3. pubmed.ncbi.nlm.nih.gov › 28760953CD318 is a ligand for CD6 - PubMed

   pubmed.ncbi.nlm.nih.gov › 28760953

   2017年8月15日 · We found that, like CD6 knockout (KO) mice, CD318 KO mice are also protected in experimental autoimmune encephalomyelitis. In humans, we found that CD318 is highly expressed in synovial tissues and participates in CD6-dependent adhesion of T cells to

4. www.pnas.org › doi › absCD318 is a ligand for CD6 - PNAS

   www.pnas.org › doi › abs

   2017年7月31日 · This report definitively establishes CD318 as a second ligand of CD6 and provides evidence for the importance of CD6–CD318 interactions in autoimmune diseases that affect the central nervous system and the synovial lining of joints.

5. www.jstor.org › stable › 26487084CD318 is a ligand for CD6

   www.jstor.org › stable › 26487084

   in experimental autoimmune encephalomyelitis. In humans, we found that CD318 is highly expressed in synovial tissues and participates in CD6-dependent adhesion of T cells to sy novial fibroblasts. In addition, soluble CD318 is chemoattractive to T cells and

6. www.researchgate.net › 318820999_CD318_is_a_ligand_for_CD6(PDF) CD318 is a ligand for CD6 - ResearchGate

   www.researchgate.net › 318820999_CD318_is_a_ligand_for_CD6

   2017年7月31日 · This report definitively establishes CD318 as a second ligand of CD6 and provides evidence for the importance of CD6–CD318 interactions in autoimmune diseases that affect the central...

7. www.ncbi.nlm.nih.gov › pmc › articlesPNAS Plus: CD318 is a ligand for CD6 - PMC - National Center ...

   www.ncbi.nlm.nih.gov › pmc › articles

   2017年8月8日 · Our results showed that CD318 is the CD6 ligand recognized by mAb 3A11 and suggest that CD318 could be a target for the diagnosis and/or treatment of autoimmune diseases such as MS and inflammatory arthritis.

   • 作者: Gospel Enyindah-Asonye, Yan Li, Jeffrey H. Ruth, Danislav S. Spassov, Katie E. Hebron, Andries Zijls...
   • DOI: 10.1073/pnas.1704008114

   • Publish Year: 2017
   • 已發佈: 2017/08/08

8. www.semanticscholar.org › paper › CD318-is-a-ligand-for-CD6[PDF] CD318 is a ligand for CD6 - Semantic Scholar

   www.semanticscholar.org › paper › CD318-is-a-ligand-for-CD6

   2017年7月31日 · This report definitively establishes CD318 as a second ligand of CD6 and provides evidence for the importance of CD6–CD318 interactions in autoimmune diseases that affect the central nervous system and the synovial lining of joints.

9. www.nature.com › articles › s41423/018/0015-1The role of CD6 in autoimmune diseases | Cellular & ...

   www.nature.com › articles › s41423/018/0015-1

   2018年3月23日 · CD166 and CD318 bind to distinct domains of CD6, and it appears possible that CD6 could bind both ligands concurrently. 16 CD6 can also interact with innate immune stimuli, including both...