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A diuretic ( / ˌdaɪjʊˈrɛtɪk /) is any substance that promotes diuresis, the increased production of urine. This includes forced diuresis. A diuretic tablet is sometimes colloquially called a water tablet. There are several categories of diuretics. All diuretics increase the excretion of water from the body, through the kidneys.
Diuresis ( / ˌdaɪjʊˈriːsɪs /) is the excretion of urine, especially when excessive ( polyuria ). The term collectively denotes the physiologic processes underpinning increased urine production by the kidneys during maintenance of fluid balance. [1]
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What is a diuretic tablet?
What is a diuretic used for?
What is an osmotic diuretic?
What is a forced diuretic tablet?
Loop diuretics are 90% bonded to proteins and are secreted into the proximal convoluted tubule through organic anion transporter 1 (OAT-1), OAT-2, and ABCC4. Loop diuretics act on the Na + -K + -2Cl − symporter (NKCC2) in the thick ascending limb of the loop of Henle to inhibit sodium, chloride and potassium reabsorption.
- High-ceiling diuretic
- Na-K-Cl cotransporter
An osmotic diuretic is a type of diuretic that inhibits reabsorption of water and sodium (Na). They are pharmacologically inert substances that are given intravenously. They increase the osmolarity of blood and renal filtrate. This fluid eventually becomes urine. and
While not classically considered potassium-sparing diuretics, ACE inhibitors (ACEis) and angiotensin receptor blockers (ARBs) are anti-hypertensive drugs with diuretic effects that decrease renal excretion of potassium. They work by inhibiting either the production (ACEis) or effects (ARBs) of angiotensin 2.
Thiazide diuretics are primarily used to treat the hypertension (high blood pressure) and edema (swelling) caused by water overload as well as certain conditions related to unbalanced calcium metabolism.
Furosemide is a loop diuretic medication used to treat edema due to heart failure, liver scarring, or kidney disease.[4] It has had many trade names including Discoid, Frusemide, Lasix and Uremide. Furosemide may also be used for the treatment of high blood pressure.[4] It can be taken intravenously or orally.[4] When given intravenously ...
