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4 天前 · Structure of a typical L-alpha-amino acid in the "neutral" form Amino acids are organic compounds that contain both amino and carboxylic acid functional groups.[1] Although over 500 amino acids exist in nature, by far the most important are the 22 α-amino acids incorporated into proteins.[2] Only these 22 appear in the genetic code of life.[3 ...
1 天前 · Metformin, sold under the brand name Glucophage, among others, is the main first-line medication for the treatment of type 2 diabetes,[12][13][14][15] particularly in people who are overweight.[13] It is also used in the treatment of polycystic ovary syndrome.[14] It is sometimes used as an off-label adjunct to lessen the risk of metabolic ...
- C₄H₁₁N₅
- AU: C
- Not by liver
- Fortamet, Glucophage, Glumetza, others
2024年5月10日 · The serpin (white) first binds a protease (grey) with the exposed reactive centre loop (blue). When this loop is cleaved by the protease, it rapidly inserts into the A-sheet (light blue), deforming and inhibiting the protease. ( PDB: 1K9O, 1EZX ) Serine and cysteine proteases operate by a two-step catalytic mechanism.
2 天前 · Paracetamol (acetaminophen[a]) is a non-opioid analgesic and antipyretic agent used to treat fever and mild to moderate pain.[13][14][15] It is a widely used over the counter medication. Common brand names include Tylenol and Panadol. At a standard dose, paracetamol only slightly reduces fever;[14][16][17] it is inferior to ibuprofen in that ...
1 天前 · Diazepam, sold under the brand name Valium among others, is a medicine of the benzodiazepine family that acts as an anxiolytic.[14] It is used to treat a range of conditions, including anxiety, seizures, alcohol withdrawal syndrome, muscle spasms, insomnia, and restless legs syndrome.[14] It may also be used to cause memory loss during certain ...
1 天前 · Wilhelm II speaking to the German people (recorded 1914) Wilhelm II [b] (Friedrich Wilhelm Viktor Albert; 27 January 1859 – 4 June 1941) was the last German Emperor and King of Prussia from 1888 until his abdication in 1918, which marked the end of the German Empire and the House of Hohenzollern 's 300-year reign in Prussia and 500-year reign ...
2 天前 · Lysergic acid diethylamide, commonly known as LSD (from German Lysergsäure-diethylamid), and known colloquially as acid or lucy, is a potent psychedelic drug.[12] Effects typically include intensified thoughts, emotions, and sensory perception.[13] At sufficiently high dosages, LSD manifests primarily mental, visual, and auditory ...