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D05295. The smallpox vaccine is the first vaccine to have been developed against a contagious disease. In 1796, British physician Edward Jenner demonstrated that an infection with the relatively mild cowpox virus conferred immunity against the deadly smallpox virus. Cowpox served as a natural vaccine until the modern smallpox vaccine emerged in ...
- AU: D
- Live virus
- ACAM2000, Imvanex, Jynneos, others
- Smallpox
Smallpox was an infectious disease caused by variola virus (often called smallpox virus), which belongs to the genus Orthopoxvirus. [7] [11] The last naturally occurring case was diagnosed in October 1977, and the World Health Organization (WHO) certified the global eradication of the disease in 1980, [10] making smallpox the only human disease ...
- 1 to 3 weeks following exposure
- Brincidofovir
- variola major virus, variola minor virus (spread between people)
- Supportive care
The history of smallpox extends into pre-history.[1] Genetic evidence suggests that the smallpox virus emerged 3,000 to 4,000 years ago.[2] Prior to that, similar ancestral viruses circulated, but possibly only in other mammals, and possibly with different symptoms. Only a few written reports dating from about 500 AD to 1000 AD are considered ...
Edward Jenner FRS FRCPE [1] (17 May 1749 – 26 January 1823) was an English physician and scientist who pioneered the concept of vaccines and created the smallpox vaccine, the world's first vaccine. [2] [3] The terms vaccine and vaccination are derived from Variolae vaccinae ('pustules of the cow'), the term devised by Jenner to denote cowpox.
Ebola, also known as Ebola virus disease (EVD) and Ebola hemorrhagic fever (EHF), is a viral hemorrhagic fever in humans and other primates, caused by ebolaviruses.[1] Symptoms typically start anywhere between two days and three weeks after infection.[3] The first symptoms are usually fever, sore throat, muscle pain, and headaches.[1] These ...
Frequency. 30 (wild) + 856 (vaccine-derived) in 2022 [4] Poliomyelitis ( / ˌpoʊlioʊˌmaɪəˈlaɪtɪs / POH-lee-oh-MY-ə-LY-tiss ), commonly shortened to polio, is an infectious disease caused by the poliovirus. [1] Approximately 75% of cases are asymptomatic; [5] mild symptoms which can occur include sore throat and fever; in a proportion ...
Human papillomavirus infection ( HPV infection) is caused by a DNA virus from the Papillomaviridae family. [5] Many HPV infections cause no symptoms and 90% resolve spontaneously within two years. [1] In some cases, an HPV infection persists and results in either warts or precancerous lesions. [2] These lesions, depending on the site affected ...
