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Methamphetamine [note 1] (contracted from N- methylamphetamine) is a potent central nervous system (CNS) stimulant that is mainly used as a recreational drug and less commonly as a second-line treatment for attention deficit hyperactivity disorder and obesity. [22] Methamphetamine was discovered in 1893 and exists as two enantiomers: levo ...
- C₁₀H₁₅N
- Desoxyn, Methedrine
20,000 civilians killed (as of October 7, 2022) [22] The Philippine drug war, known as the War on Drugs, is the intensified anti-drug campaign that began during the administration of President Rodrigo Duterte, who served office from June 30, 2016, to June 30, 2022. The campaign reduced drug proliferation in the country, [23] but has been marred ...
- July 1, 2016 – present, (7 years, 2 months and 19 days)
- Ongoing
- Philippines
Botulinum toxin, or botulinum neurotoxin (commonly called botox), is a highly potent neurotoxic protein produced by the bacterium Clostridium botulinum and related species.[23] It prevents the release of the neurotransmitter acetylcholine from axon endings at the neuromuscular junction, thus causing flaccid paralysis.[24] The toxin causes the ...
Breaking Bad. Breaking Bad is an American crime drama television series created and produced by Vince Gilligan for AMC. Set and filmed in Albuquerque, New Mexico, the series follows Walter White ( Bryan Cranston ), an underpaid, dispirited high-school chemistry teacher struggling with a recent diagnosis of stage-three lung cancer. White turns ...
- 5
- 62 (list of episodes)
- January 20, 2008 –, September 29, 2013
- AMC
- Signs and Symptoms
- Cause
- Mechanism
- Diagnosis
- Prevention
- Treatment
- Prognosis
- Other Susceptible Species
- Use in Biological Warfare and Terrorism
- See Also
The muscle weakness of botulism characteristically starts in the muscles supplied by the cranial nerves—a group of twelve nerves that control eye movements, the facial muscles and the muscles controlling chewing and swallowing. Double vision, drooping of both eyelids, loss of facial expression and swallowing problems may therefore occur. In additio...
Clostridium botulinum is an anaerobic, Gram-positive, spore-forming rod. Botulinum toxin is one of the most powerful known toxins: about one microgram is lethal to humans when inhaled. It acts by blocking nerve function (neuromuscular blockade) through inhibition of the excitatory neurotransmitter acetylcholine's release from the presynaptic membra...
The toxin is the protein botulinum toxin produced under anaerobic conditions (where there is no oxygen) by the bacterium Clostridium botulinum. Clostridium botulinum is a large anaerobic Gram-positive bacillus that forms subterminal endospores. There are eight serological varieties of the bacterium denoted by the letters A to H. The toxin from all ...
For botulism in babies, diagnosis should be made on signs and symptoms. Confirmation of the diagnosis is made by testing of a stool or enema specimen with the mouse bioassay. In people whose history and physical examination suggest botulism, these clues are often not enough to allow a diagnosis. Other diseases such as Guillain–Barré syndrome, strok...
Although the vegetative form of the bacteria is destroyed by boiling,the spore itself is not killed by the temperatures reached with normal sea-level-pressure boiling, leaving it free to grow and again produce the toxin when conditions are right. A recommended prevention measure for infant botulism is to avoid giving honey to infants less than 12 m...
Botulism is generally treated with botulism antitoxinand supportive care. Supportive care for botulism includes monitoring of respiratory function. Respiratory failure due to paralysis may require mechanical ventilation for 2 to 8 weeks, plus intensive medical and nursing care. After this time, paralysis generally improves as new neuromuscular conn...
The paralysis caused by botulism can persist for two to eight weeks, during which supportive care and ventilation may be necessary to keep the patient alive. Botulism can be fatal in five to ten percent of people who are affected.However, if left untreated, botulism is fatal in 40 to 50 percent of cases. Infant botulism typically has no long-term s...
Botulism can occur in many vertebrates and invertebrates. Botulism has been reported in such species as rats, mice, chicken, frogs, toads, goldfish, aplysia, squid, crayfish, drosophilaand leeches. Death from botulism is common in waterfowl; an estimated 10,000 to 100,000 birds die of botulism annually. The disease is commonly called "limberneck". ...
United States
Based on CIA research in Fort Detrick on biological warfare, anthrax and botulism were widely regarded as the two most effective options. During the 1950s, a highly lethal strain was discovered during the biological warfare program. The CIA continued to hold 5 grams of Clostridium botulinum, even after Nixon's ban on biological warfare in 1969. During the Gulf War, when the United States were concerned with a potential biowarfare attack, the efforts around botulism turned to prevention. Howev...
Iraq
Iraq has historically possessed many types of germs, including botulism. The American Type Culture Collection sold 5 variants of botulinum to the University of Baghdad in May 1986. 1991 CIA reports also show Iraqis filled shells, warheads, and bombs with biological agents like botulinum (though none have been deployed).The Iraqi air force used the code name "tea" to refer to botulinum, and it was also referred to as bioweapon "A."
Japan
A Japanese cult called Aum Shinrikyo created laboratories that produced biological weapons, specifically botulinum, anthrax, and Q fever. From 1990 to 1995, the cult staged numerous unsuccessful bioterrorism attacks on civilians.They sprayed botulinum toxin from a truck in downtown Tokyo and in the Narita airport, but there are no reported cases of botulism as a result.
- 12 to 72 hours
- Weakness, trouble seeing, feeling tired, trouble speaking
Budget. US$25 million. Box office. US$200 million [1] The White Storm 2: Drug Lords is a 2019 Hong Kong action film directed by Herman Yau, produced by and starring Andy Lau. The film is a thematic sequel in-title-only to the 2013 film The White Storm with a new storyline and stars returning cast member Louis Koo in a different role.
Griselda Blanco Restrepo [2] (February 15, 1943 – September 3, 2012) was a Colombian drug lord who was prominent in the cocaine -based drug trade and underworld of Miami, during the 1970s through the early 2000s, and who has also been claimed by some to have been part of the Medellín Cartel.
