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Oral Fansidar (sulfadoxine and pyrimethamine) has not been evaluated for the treatment of cerebral malaria or other severe manifestations of complicated malaria, including hyperparasitemia, pulmonary edema or renal failure. Patients with severe malaria are not candidates for oral therapy. In the event of recrudescent P. falciparuminfections after t...
Regularly scheduled complete blood counts, liver enzyme tests and analysis of urine for crystalluria should be performed whenever Fansidar (sulfadoxine and pyrimethamine) is administered for more than three months.
Pyrimethamine was not found carcinogenic in female mice or in male and female rats. The carcinogenic potential of pyrimethamine in male mice could not be assessed from the study because of markedly reduced life-span. Pyrimethamine was found to be mutagenic in laboratory animals and also in human bone marrowfollowing 3 or 4 consecutive daily doses t...
Fansidar (sulfadoxine and pyrimethamine) has been shown to be teratogenicin rats when given in weekly doses approximately 12 times the weekly human prophylactic dose. Teratology studies with pyrimethamine plus sulfadoxine (1:20) in rats showed the minimum oral teratogenic dose to be approximately 0.9 mg/kg pyrimethamine plus 18 mg/kg sulfadoxine. I...
Fansidar (sulfadoxine and pyrimethamine) should not be given to infants less than 2 months of age because of inadequate development of the glucuronide-forming enzyme system.
Clinical studies of Fansidar (sulfadoxine and pyrimethamine) did not include sufficient numbers of subjects aged 65 and over to determine whether they respond differently from younger subjects. Other reported clinical experience has not identified differences in responses between the elderly and younger patients. In general, dose selection for an e...
2017年5月25日 · Recommended Dosage. The recommended dosage of PLETAL is 100 mg twice daily taken at least half an hour before or two hours after breakfast and dinner. Patients may respond as early as 2 to 4 weeks after the initiation of therapy, but treatment for up to 12 weeks may be needed before a beneficial effect is experienced.
2022年5月16日 · Adults. The usual initial antihypertensive oral dose of NORVASC is 5 mg once daily, and the maximum dose is 10 mg once daily. Small, fragile, or elderly patients, or patients with hepatic insufficiency may be started on 2.5 mg once daily and this dose may be used when adding NORVASC to other antihypertensive therapy.
2023年12月18日 · dry mouth, sore throat, hoarseness, eye redness, blurred vision, nosebleed, or. skin rash. Tell your doctor if you experience serious side effects of Claritin including fast or uneven heart rate, feeling like you might pass out, jaundice (yellowing of your skin or eyes), or seizures (convulsions). Claritin may cause serious side effects including:
The usual dose of oral KEFLEX is 250 mg every 6 hours, but a dose of 500 mg every 12 hours may be administered. Treatment is administered for 7 to 14 days. For more severe infections larger doses of oral KEFLEX may be needed, up to 4 grams daily in two to four equally divided doses.
2023年3月24日 · The recommended starting dose of Levitra is 10 mg, taken orally, as needed, approximately 60 minutes before sexual activity. The dose may be increased to a maximum 20 mg or decreased to 5 mg based on efficacy and side effects. The maximum recommended dosing frequency is once per day.
