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- Overview
- How to Prepare for the Test
- How the Test will Feel
- Why the Test is Performed
- Normal Results
- What Abnormal Results Mean
- Risks
The immunofixation blood test is used to identify proteins called immunoglobulins in blood. Immunoglobulins are proteins that function as antibodies, which fight infection. There are many types of immunoglobulins that fight different types of infections. Some immunoglobulins can be abnormal and may be due to cancer.
There is no special preparation for this test.
When the needle is inserted to draw blood, some people feel moderate pain. Others feel only a prick or stinging. Afterward, there may be some throbbing or a slight bruise. This soon goes away.
This test is most often used to check the levels of antibodies when certain cancers and other disorders are present or suspected.
A normal (negative) result means that the blood sample had normal types of immunoglobulins. The level of one immunoglobulin was not higher than any other.
An abnormal result may be due to:
•Amyloidosis (buildup of abnormal proteins in tissues and organs)
•Leukemia or Waldenström macroglobulinemia (types of white blood cell cancers)
•Lymphoma (cancer of the lymph tissue)
•Monoclonal gammopathy of unknown significance (MGUS)
•Multiple myeloma (a type of blood cancer)
There is little risk involved with having your blood taken. Veins and arteries vary in size from one person to another and from one side of the body to the other. Taking blood from some people may be more difficult than from others.
Other risks associated with having blood drawn are slight, but may include:
•Excessive bleeding
•Fainting or feeling lightheaded
•Multiple punctures to locate veins
•Hematoma (blood accumulating under the skin)
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