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Vitamin D is a group of fat-soluble secosteroids responsible for increasing intestinal absorption of calcium, magnesium, and phosphate, and for many other biological effects.[1][2][3] In humans, the most important compounds in this group are vitamin D3 (cholecalciferol) and vitamin D2 (ergocalciferol).[2][3][4] The major natural source of ...
- Calciferols
- vitamin D receptor
Vitamin D deficiency or hypovitaminosis D is a vitamin D level that is below normal. It most commonly occurs in people when they have inadequate exposure to sunlight, particularly sunlight with adequate ultraviolet B rays (UVB).[1][2][3] Vitamin D deficiency can also be caused by inadequate nutritional intake of vitamin D; disorders that limit ...
- Usually asymptomatic
- Supplements
Ergocalciferol is a secosteroid formed by a photochemical bond breaking of a steroid, specifically, by the action of ultraviolet light (UV-B or UV-C) on ergosterol, a form of provitamin D 2. [19] Like cholecalciferol, ergocalciferol is inactive by itself. It requires two hydroxylations to become active: the first in the liver by CYP2R1 to form ...
The vitamin D receptor ( VDR also known as the calcitriol receptor) is a member of the nuclear receptor family of transcription factors. [5] Calcitriol (the active form of vitamin D, 1,25- (OH) 2 vitamin D 3) binds to VDR, which then forms a heterodimer with the retinoid-X receptor. The VDR heterodimer then enters the nucleus and binds to ...
The name 25 (OH)D refers to any combination of calcifediol (25-hydroxy-cholecalciferol), derived from vitamin D 3, and ercalcidiol (25-hydroxy-ergocalciferol), [1] derived from vitamin D 2. The first of these (also known as 25-hydroxy vitamin D3) is made by the body, or is sourced from certain animal foods or cholecalciferol supplements.
Andrew David Huberman (born September 26, 1975) is an American neuroscientist and podcaster.He is an associate professor of neurobiology and ophthalmology at the Stanford University School of Medicine.Since 2021, he has hosted the Huberman Lab podcast, which despite its popularity has attracted criticism for promoting poorly supported health claims.
Dissociative identity disorder is characterized by the presence of at least two distinct and relatively enduring personality states. [3] [25] (p331) The disorder is accompanied by memory gaps more severe than could be explained by ordinary forgetfulness. [3] [25] (p331) [26] The personality states alternately show in a person's behavior; [3 ...