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Thalidomide, sold under the brand names Contergan and Thalomid among others, is an oral medication used to treat a number of cancers ( e.g., multiple myeloma ), graft-versus-host disease, and many skin disorders ( e.g., complications of leprosy such as skin lesions ). [6] [7] [8] While thalidomide has been used in a number of HIV -associated ...
- C₁₃H₁₀N₂O₄
- Contergan, Thalomid, others
- AU: X (High risk)
- By mouth
Methylphenidate, sold under the brand names Ritalin (/ˈrɪtəlɪn/ RIT-ə-lin) and Concerta (/kənˈsɜːrtə/ kən-SUR-tə) among others, is a potent central nervous system (CNS) stimulant used medically to treat attention deficit hyperactivity disorder (ADHD) and, to a lesser extent, narcolepsy. It is a primary medication for ADHD (e.g. in ...
- C₁₄H₁₉NO₂
- Ritalin, Concerta, others
- AU: D
Oxycodone, sold under various brand names such as Roxicodone and OxyContin (which is the extended release form), is a semi-synthetic opioid used medically for treatment of moderate to severe pain. It is highly addictive[14] and is a commonly abused drug.[15][16] It is usually taken by mouth, and is available in immediate-release and controlled ...
- By mouth: 60–87%
- AU: C
- C₁₈H₂₁NO₄
- OxyContin, Endone, others
Fentanyl is a highly potent synthetic piperidine opioid primarily used as an analgesic. It is 20 to 40 times more potent than heroin and 100 times more potent than morphine; [8] its primary clinical utility is in pain management for cancer patients and those recovering from painful surgeries. [9] [10] Fentanyl is also used as a sedative. [11]
- C₂₂H₂₈N₂O
- Actiq, Duragesic, Sublimaze, others
- AU: C
Metformin, sold under the brand name Glucophage, among others, is the main first-line medication for the treatment of type 2 diabetes,[12][13][14][15] particularly in people who are overweight.[13] It is also used in the treatment of polycystic ovary syndrome.[14] It is sometimes used as an off-label adjunct to lessen the risk of metabolic ...
- C₄H₁₁N₅
- AU: C
- Not by liver
- Fortamet, Glucophage, Glumetza, others
Lysergic acid diethylamide, commonly known as LSD (from German Lysergsäure-diethylamid), and known colloquially as acid or lucy, is a potent psychedelic drug.[12] Effects typically include intensified thoughts, emotions, and sensory perception.[13] At sufficiently high dosages, LSD manifests primarily mental, visual, and auditory ...
Dopamine (DA, a contraction of 3,4-dihydroxyphenethylamine) is a neuromodulatory molecule that plays several important roles in cells. It is an organic chemical of the catecholamine and phenethylamine families. Dopamine constitutes about 80% of the catecholamine content in the brain. It is an amine synthesized by removing a carboxyl group from ...