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B vitamins are a class of water-soluble vitamins that play important roles in cell metabolism and synthesis of red blood cells. [1][2] They are a chemically diverse class of compounds. [1] Dietary supplements containing all eight are referred to as a vitamin B complex.
Vitamin B 12, also known as cobalamin, is a water-soluble vitamin involved in metabolism. [2] It is one of eight B vitamins. It is required by animals, which use it as a cofactor in DNA synthesis, and in both fatty acid and amino acid metabolism. [3]
BLE. Bilateral Lower Extremity (in/on both legs). BLS. basic life support. BM. bone marrow. bowel movement. breast milk. Capillary blood glucose (British medical colloquialism originating from Boehringer Mannheim, a manufacturer of early glucose meters, today a part of Boehringer Ingelheim.)
- Development and Structure of The B Cell Receptor
- Signaling Pathways of The B Cell Receptor
- The B-Cell Receptor in Malignancy
The first checkpoint in the development of a B cell is the production of a functional pre-BCR, which is composed of two surrogate light chains and two immunoglobulin heavy chains, which are normally linked to Ig-α (or CD79A) and Ig-β (or CD79B) signaling molecules. Each B cell, produced in the bone marrow, is highly specific to an antigen.The BCR c...
There are several signaling pathways that the B-cell receptor can follow through. The physiology of B cells is intimately connected with the function of their B-cell receptor. The BCR signaling pathway is initiated when the mIg subunits of the BCR bind a specific antigen. The initial triggering of the BCR is similar for all receptors of the non-cat...
The B-cell receptor has been shown to be involved in the pathogenesis of various B cell derived lymphoid cancers. Although it may be possible that stimulation by antigen binding contributes to the proliferation of malignant B cells, increasing evidence implicates antigen-independent self-association of BCRs as a key feature in a growing number of B...
In immunology, a memory B cell (MBC) is a type of B lymphocyte that forms part of the adaptive immune system. These cells develop within germinal centers of the secondary lymphoid organs. Memory B cells circulate in the blood stream in a quiescent state [1]
Haplogroup B (M60) is a human Y-chromosome DNA haplogroup common to paternal lineages in Africa. It is a primary branch of the haplogroup BT. B (M60) is common in parts of Africa, especially the tropical forests of West-Central Africa.
Function. Apolipoprotein B is the primary apolipoprotein of chylomicrons, VLDL, Lp (a), IDL, and LDL particles (LDL—commonly known as "bad cholesterol " when in reference to both heart disease and vascular disease in general), which is responsible for carrying fat molecules (lipids), including cholesterol, around the body to all ...
