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  1. www.ncbi.nlm.nih.gov › pmc › articlesHuman Papillomavirus E6 and E7: The Cervical Cancer ...

    2020年1月21日 · Human papillomavirus (HPV)-induced cervical cancer is a major health issue among women from the poorly/under-developed sectors of the world. It accounts for a high-mortality rate because of its late diagnosis and poor prognosis.

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  3. www.ncbi.nlm.nih.gov › pmc › articlesHuman papillomavirus E6 and E7: What remains? - PMC

    2021年2月8日 · Since HPV E7 phosphorylation appears to play a fundamental role in E7 functions and stability, it is important to elucidate whether other kinases are involved during HPV infection and malignancy, how they are regulated, and which pathways and cellular targets

    • Arushi Vats, Oscar Trejo-Cerro, Miranda Thomas, Lawrence Banks
    • 10.1016/j.tvr.2021.200213
    • 2021
    • Tumour Virus Res. 2021 Jun; 11: 200213.

  4. www.nature.com › articles › s41417/023/00682-3HPV E6/E7: insights into their regulatory role and mechanism ...

    2023年12月15日 · 1 Altmetric. Metrics. Abstract. Human papillomavirus (HPV) is a class of envelope-free double-stranded DNA virus. HPV infection has been strongly associated with the development of many...

  5. www.ncbi.nlm.nih.gov › pmc › articlesThe Not-So-Good, the Bad and the Ugly: HPV E5, E6 and E7 ...

    2021年9月22日 · HPVs cause almost one-third of the 15.4% human cancers attributable to carcinogenic infections [ 3 ]. Cervical cancer charts as the second-most common cancer in women aged 15–44 years and the fourth leading cause of female cancer worldwide, and cervical cancer is almost always associated with infection with HPVs [ 5 ].

    • Om Basukala, Lawrence Banks
    • 2021

  6. www.hpa.gov.tw › Pages › Detail衛生福利部國民健康署 - 完整接種HPV疫苗 守護寶貝的健康

    2024年2月21日 · 罹患子宮頸癌的主要原因是持續感染人類乳突病毒（HPV），一般感染HPV後，沒有明顯症狀，約有9成感染者會在1年內自行消除，而超過1年未消除就稱為「持續性感染」。 根據世界衛生組織（WHO）建議，針對9-14歲性行為尚未活躍女性接種HPV疫苗，預防效果較佳。 國民健康署自107年12月底開始，全面推動國中女生接種HPV疫苗的服務，截至113年1月，107-110年入學國中女生完整接種2劑之涵蓋率分別為75.0%、85.9%、86.0%、91.3%，逐年上升，並朝接種率穩定達90%以上之目標前進，鼓勵符合資格者接種疫苗，建構起健康的防線。 HPV疫苗接種「前、中、後」注意事項.

  7. www.nature.com › articles › s41388/020/01431-8HPV E2, E4, E5 drive alternative carcinogenic pathways in ...

    2020年8月26日 · 49 Citations. 2 Altmetric. Metrics. Abstract. The dominant paradigm for HPV carcinogenesis includes integration into the host genome followed by expression of E6 and E7 (E6/E7). We explored...

  8. www.nature.com › articles › s41598/023/42022-3Increased expression of HPV-E7 oncoprotein correlates with a ...

    2023年9月12日 · Scientific Reports - Increased expression of HPV-E7 oncoprotein correlates with a reduced level of pRb proteins via high viral load in cervical cancer