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Hydrochlorothiazide, sold under the brand name Hydrodiuril among others, is a diuretic medication used to treat hypertension and swelling due to fluid build-up. Other uses include treating diabetes insipidus and renal tubular acidosis and to decrease the risk of kidney stones in those with a high calcium level in the urine . [4]
- C₇H₈ClN₃O₄S₂
- AU: C
- Not significant
- Hydrodiuril, others
Chlorothiazide, sold under the brand name Diuril among others, is an organic compound used as a diuretic and as an antihypertensive.[1][2] It is used both within the hospital setting or for personal use to manage excess fluid associated with congestive heart failure. Most often taken in pill form, it is usually taken orally once or twice a day ...
- C₇H₆ClN₃O₄S₂
- By mouth, IV
- Nil
- Diuril, others
Thiazide diuretics are primarily used to treat the hypertension (high blood pressure) and edema (swelling) caused by water overload as well as certain conditions related to unbalanced calcium metabolism.
Examples. Enalapril/hydrochlorothiazide (trade name Enalapril comp), wherein enalapril is the ACE inhibitor and hydrochlorothiazide is the thiazide. Quinapril /hydrochlorothiazide (trade name Accuretic) [2] Lisinopril/hydrochlorothiazide is marketed as Prinzide, [3] Zestoretic, [4] and many others.
- Accuretic
- Angiotensin converting enzyme inhibitor
- US: ℞-only
Olmesartan/hydrochlorothiazide, sold under the brand name Benicar HCT among others, is a fixed-dose combination medication used to treat high blood pressure. It is a combination of olmesartan medoxomil, an angiotensin II receptor blocker and , a diuretic.
- Benicar HCT, Benitec H, others
- By mouth
Calcium channel blockers ( CCB ), calcium channel antagonists or calcium antagonists [2] are a group of medications that disrupt the movement of calcium ( Ca2+. ) through calcium channels. [3] Calcium channel blockers are used as antihypertensive drugs, i.e., as medications to decrease blood pressure in patients with hypertension.
The thiazide-like diuretics (indapamide and chlorthalidone) reduce risk of major cardiovascular events and heart failure in hypertensive patients compared with hydrochlorothiazide with a comparable incidence of adverse events. Both thiazide diuretics and thiazide