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2024年4月8日 · SARS, highly contagious respiratory illness characterized by a persistent fever, headache, and bodily discomfort, followed by a dry cough that may progress to great difficulty in breathing. SARS first appeared in November 2002 in Guangdong province, China, and a specific vaccine for it has not yet been developed.
- The Editors of Encyclopaedia Britannica
4 天前 · In turn, SARS-CoV-2 persistence might result in long COVID symptoms through direct host-cell changes, immune activation, latent virus reactivation, or combinations of the three. From an immune activation perspective, recent studies have found that patients with long COVID have complement dysregulation with signs of thromboinflammation, higher ...
1 天前 · Abstract. SARS-CoV-2 can infect various human tissues and cell types, principally via interaction with its cognate receptor ACE2. However, how the virus evolves in different cellular environments is poorly understood. Here, we used experimental evolution to study the adaptation of the SARS-CoV-2 spike to four human cell lines expressing ...
4 天前 · COVID-19 is caused by the coronavirus known as SARS-CoV-2. There is no cure for COVID-19, but individuals can be protected against severe illness through vaccination. Learn about the symptoms, treatment, and prevention of COVID-19.
- The Editors of Encyclopaedia Britannica
3 天前 · This is consistent with the persistence of SARS-CoV-2 circulation in populations with high vaccination coverage and resulting value of direct protection. Results for individuals aged 6 to 59 months differed from those of older age groups in that we found a significant reduction in hospitalizations, but not cases, following vaccination.
2 天前 · The spike protein is very large, often 1200 to 1400 amino acid residues long; [8] it is 1273 residues in SARS-CoV-2. [5] It is a single-pass transmembrane protein with a short C-terminal tail on the interior of the virus, a transmembrane helix, and a large N-terminal ectodomain exposed on the virus exterior. [5] [7]
3 天前 · SARS-CoV-2 infection can be associated with ‘brain fog’ and persistent neurologic disease, especially in the elderly, with the possibility of direct viral particle interference with normal ...
